From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Treatment for acute urinary bladder spasms typically involves anticholinergic medications such as oxybutynin (5-10mg two to three times daily), tolterodine (2mg twice daily), or solifenacin (5-10mg once daily) as the first line of treatment. These medications work by blocking acetylcholine receptors in the bladder muscle, reducing involuntary contractions that cause spasms 1. For immediate relief, antispasmodic medications like flavoxate (100-200mg three to four times daily) or hyoscyamine (0.125-0.25mg every 4 hours) may be prescribed. Some key points to consider in the treatment of acute urinary bladder spasms include:
- Warm baths, heating pads applied to the lower abdomen, and avoiding bladder irritants such as caffeine, alcohol, spicy foods, and acidic beverages can help reduce symptoms.
- Adequate hydration is important, but patients should avoid excessive fluid intake, especially before bedtime.
- In some cases, phenazopyridine (100-200mg three times daily) may be used for pain relief.
- If spasms are related to a urinary tract infection, appropriate antibiotics will be necessary.
- For severe cases unresponsive to oral medications, bladder instillations with lidocaine or muscle relaxants may be considered under medical supervision 2, 3. It's also important to note that the choice of anticholinergic therapy should be guided by individual patient comorbidities, as objective efficacy of anticholinergic drugs is similar 1. In terms of specific medication choices, solifenacin (5-10mg once daily) may be a good option for elderly patients or those with pre-existing cognitive dysfunction, while darifenacin may be suitable for patients with pre-existing cardiac concerns or cognitive dysfunction 1.