Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 19, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Pelvic Pain and Irregular Menstruation

The patient's symptoms of pelvic pain, irregular menstruation, and pain with sexual intercourse can be caused by various conditions. Here's a categorized differential diagnosis:

  • Single most likely diagnosis

    • Endometriosis: This condition is characterized by the growth of endometrial tissue outside the uterus, leading to pelvic pain, irregular menstruation, and dyspareunia (pain with sexual intercourse). The patient's symptoms align closely with the typical presentation of endometriosis.
  • Other Likely diagnoses

    • Pelvic Inflammatory Disease (PID): PID can cause pelvic pain, irregular menstrual bleeding, and dyspareunia. It is often associated with sexually transmitted infections.
    • Uterine Fibroids: These benign tumors can cause pelvic pain, heavy or irregular menstrual bleeding, and dyspareunia due to pressure on surrounding structures.
    • Adenomyosis: This condition, where endometrial tissue grows into the uterine wall, can lead to pelvic pain, heavy or irregular menstrual bleeding, and dyspareunia.
  • Do Not Miss diagnoses

    • Ectopic Pregnancy: Although less likely given the patient's age and presentation, an ectopic pregnancy can cause pelvic pain and irregular vaginal bleeding. It is a medical emergency that requires immediate attention.
    • Ovarian Torsion: This condition involves the twisting of an ovary, which can cause severe pelvic pain. It is a surgical emergency.
    • Appendicitis: While appendicitis typically presents with abdominal pain, it can sometimes cause pelvic pain if the appendix is located near the pelvic organs.
  • Rare diagnoses

    • Ovarian Cancer: Although rare in a 37-year-old woman, ovarian cancer can cause pelvic pain, irregular vaginal bleeding, and dyspareunia.
    • Interstitial Cystitis: This condition, also known as bladder pain syndrome, can cause chronic pelvic pain, often accompanied by urinary frequency and urgency.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.