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Last updated: July 20, 2025View editorial policy

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Differential Diagnosis for Sore in Nare

Single Most Likely Diagnosis

  • Nasal Vestibulitis: This is an inflammation of the nasal vestibule, often caused by bacterial infections such as Staphylococcus aureus. It's a common condition that can cause a sore or painful sensation in the nare.

Other Likely Diagnoses

  • Folliculitis: An inflammation of the hair follicles in the nose, which can be caused by bacterial or fungal infections. It presents with small, pus-filled bumps and can be painful.
  • Furuncle or Boil: A localized skin infection, usually caused by Staphylococcus aureus, that can occur in the nose. It appears as a painful nodule or pustule.
  • Nasal Dryness or Irritation: Dry air, allergies, or irritants can cause soreness and discomfort in the nasal area.

Do Not Miss Diagnoses

  • Nasal Septal Perforation: Although less common, a perforation in the nasal septum can cause pain, crusting, and bleeding. It's crucial to diagnose and treat to prevent further complications.
  • Squamous Cell Carcinoma or Other Malignancies: Though rare, any persistent or non-healing sore in the nasal area should be biopsied to rule out cancer.
  • Invasive Fungal Sinusitis: Especially in immunocompromised patients, this can present with nasal pain, discharge, and facial pain. It's life-threatening if not promptly treated.

Rare Diagnoses

  • Leprosy (Hansen's Disease): A chronic bacterial infection that can affect the skin and nerves, including those in the nasal area, causing sores and lesions.
  • Granuloma Faciale: A rare skin condition characterized by single or multiple nodules, usually on the face, including the nose, which can be painful.
  • Wegener's Granulomatosis (Granulomatosis with Polyangiitis): A rare autoimmune disorder that can cause inflammation of the blood vessels, including those in the nasal area, leading to sores and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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