Mitigating Opioid Use and Promoting Alternative Pain Management Approaches
Nonopioid therapies should be maximized as first-line treatment for subacute and chronic pain, with opioids considered only when expected benefits for pain and function outweigh risks to the patient. 1
Evidence-Based Strategies for Reducing Opioid Prescribing
Patient Risk Assessment and Education
Perform thorough risk assessment before prescribing opioids:
- Use validated screening tools like Drug Abuse Screening Test (DAST) and Alcohol Use Disorders Identification Test (AUDIT) 1
- Ask direct questions about past substance use: "How many times in the past year have you used an illegal drug or used a prescription medication for nonmedical reasons?" 1
- Check Prescription Drug Monitoring Program (PDMP) data to identify potential doctor shopping 1
Provide comprehensive patient education:
- Discuss realistic benefits and known risks of opioid therapy 1
- Explain that pain management goal is to make pain manageable rather than eliminate it completely 1
- Emphasize increased risks of respiratory depression when opioids are combined with benzodiazepines, other sedatives, or alcohol 1, 2
- Educate about safe storage and disposal of medications 1
Implementing Alternative Pain Management Approaches
Recommend evidence-based nonpharmacologic approaches:
- Exercise therapy for back pain, fibromyalgia, and osteoarthritis
- Weight loss for knee osteoarthritis
- Manual therapies for hip osteoarthritis
- Psychological therapy, mindfulness-based stress reduction, yoga, and acupuncture for low back pain
- Cognitive behavioral therapy for fibromyalgia 1
Utilize multimodal nonopioid pharmacologic options:
Strategies for Healthcare Systems and Providers
Changing Prescribing Practices
Implement opioid prescribing and dispensing policies:
Use opioid patient-provider agreements (PPAs) that include:
- Informed consent component
- Clear plan of care
- Expectations for follow-up and monitoring 1
Monitoring and Risk Mitigation
Conduct routine monitoring of patients on opioid therapy:
Consider naloxone prescriptions for high-risk patients:
- Those with history of overdose
- Patients with substance use disorders
- Patients taking benzodiazepines with opioids 1
Convincing Reluctant Stakeholders
For Patients Resistant to Alternative Approaches
- Frame discussions around quality of life and function rather than just pain intensity
- Emphasize that opioids often become less effective over time due to tolerance
- Discuss opioid-related side effects that can worsen quality of life (constipation, nausea, cognitive effects)
- Share evidence that multimodal approaches often provide better long-term outcomes 3
- Use motivational interviewing techniques to address resistance
For Prescribers Resistant to Change
- Present evidence that comprehensive pain management systems reduce opioid prescribing while improving pain control 4, 5
- Highlight that 82% of clinicians report reluctance to prescribe opioids, suggesting awareness of risks 1
- Share success stories like the 95% reduction in brand name opioid-acetaminophen products achieved by Kaiser Permanente Southern California 4
- Emphasize that multimodal protocols have shown improved pain scores while reducing opioid use 5
Special Considerations
For Patients Already on Opioid Therapy
- Don't abruptly discontinue opioids in patients physically dependent on them
- Gradually taper doses when risks outweigh benefits
- Provide emotional support, close monitoring, and reassessment during tapering 1
- Link patients to addiction treatment and mental health services when indicated 1
For Patients with History of Substance Use Disorder
- Apply a universal precautions approach that views controlled substances as medications with unique risks to every patient 1
- Consider consultation with substance use disorder specialists and pain specialists 1
- For patients on medication-assisted treatment (methadone/buprenorphine):
- Continue maintenance dose of opioid agonist therapy
- Use short-acting opioid analgesics if needed for acute pain
- Verify doses with treatment program 1
Common Pitfalls to Avoid
- Equating requests for pain medication with drug-seeking behavior
- Failing to address underlying anxiety about pain management
- Abruptly discontinuing opioids in physically dependent patients
- Relying solely on opioid contracts without providing alternative pain management options
- Using urine drug test results in isolation to discharge patients from care 1
- Neglecting to consider how cultural factors may influence pain expression and treatment preferences
By implementing these evidence-based strategies, healthcare providers can effectively mitigate opioid use while ensuring adequate pain management for patients with chronic pain conditions.