From the Guidelines
The recommended dosage of Tadalafil (Cialis) for erectile dysfunction is 10mg taken before sexual activity, which can be adjusted to 5mg or increased to 20mg based on individual response, as supported by the study published in the Annals of Internal Medicine 1.
Dosage Considerations
When considering the dosage of Tadalafil, it's essential to take into account the individual's response to the medication. The study found that improvement in erectile function was related to higher doses for some medications, but not for Tadalafil (20 mg vs. 10 mg vs. 5 mg) 1.
Potential Interactions and Side Effects
It's crucial to note that Tadalafil should not be taken with nitrates or certain other medications due to potential dangerous interactions that could cause a severe drop in blood pressure. Common side effects include headache, indigestion, back pain, muscle aches, flushing, and nasal congestion. Patients with kidney or liver impairment may require lower doses, and it's essential to follow the healthcare provider's instructions for taking the medication.
Comparison with Other Treatments
The study also compared Tadalafil with other treatments, including sildenafil, and found that the evidence was insufficient to determine whether one treatment was more effective than the other 1. However, this does not affect the recommended dosage of Tadalafil.
Important Considerations
Tadalafil should be taken as directed by your healthcare provider, with or without food. The medication works by inhibiting the enzyme phosphodiesterase type 5, which increases blood flow to certain areas of the body. For daily use, 2.5mg or 5mg once daily is recommended, and for benign prostatic hyperplasia, 5mg once daily is the standard dose. For pulmonary arterial hypertension, 40mg once daily is typically prescribed.
From the FDA Drug Label
The recommended starting dose of tadalafil tablets for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity. The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability. The recommended starting dose of tadalafil tablets for once daily use is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity. The tadalafil tablets dose for once daily use may be increased to 5 mg, based on individual efficacy and tolerability. The recommended dose of tadalafil tablets for once daily use for Benign Prostatic Hyperplasia is 5 mg, taken at approximately the same time every day. The recommended dose of tadalafil tablets for once daily use for Erectile Dysfunction and Benign Prostatic Hyperplasia is 5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.
The recommended dosage of Tadalafil (Cialis) is:
- For use as needed: 10 mg, taken prior to anticipated sexual activity, with a maximum dose of 20 mg and a minimum dose of 5 mg.
- For once daily use:
- For Erectile Dysfunction: 2.5 mg, taken at approximately the same time every day, with a maximum dose of 5 mg.
- For Benign Prostatic Hyperplasia: 5 mg, taken at approximately the same time every day.
- For Erectile Dysfunction and Benign Prostatic Hyperplasia: 5 mg, taken at approximately the same time every day. 2
From the Research
Recommended Dosage of Tadalafil (Cialis)
The recommended dosage of Tadalafil (Cialis) can vary depending on the condition being treated.
- For erectile dysfunction, the typical starting dose is 10mg, taken as needed, prior to anticipated sexual activity 3.
- However, the dose can be adjusted based on efficacy and tolerability, with options for 5mg or 20mg 3.
- For once-daily dosing, 5mg is a common dose, which has been shown to be effective and well-tolerated in clinical trials 4, 5.
- In patients with benign prostatic hyperplasia (BPH), 5mg of tadalafil once daily has been shown to improve lower urinary tract symptoms and erectile function 5, 6.
Key Considerations
- The dosage of tadalafil should be individualized based on the patient's response and tolerability.
- Patients should be advised to take the medication as directed, and not to exceed the recommended dose.
- Tadalafil can be taken with or without food, and the dose should not be adjusted based on food intake.
- The medication should not be taken more than once daily, as this can increase the risk of adverse effects.
Adverse Effects
- Common adverse effects of tadalafil include headache, dyspepsia, back pain, and nasopharyngitis 4, 5, 3.
- Serious adverse effects are rare, but can include priapism, sudden vision loss, and sudden hearing loss 3.
- Patients should be advised to seek medical attention if they experience any adverse effects, especially if they are severe or persistent.