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Differential Diagnosis for a Small Round Lump on the Scalp

Single Most Likely Diagnosis

  • Folliculitis: A common condition characterized by inflammation of the hair follicles, often caused by bacterial or fungal infections. The tender, flesh-colored lump on the scalp is consistent with folliculitis, especially given its small size and tenderness to touch.

Other Likely Diagnoses

  • Epidermoid Cyst: A benign cyst that can occur on the scalp, often appearing as a small, round, flesh-colored lump. These cysts can become inflamed and tender, fitting the description provided.
  • Sebaceous Cyst: Similar to epidermoid cysts, sebaceous cysts are benign and can appear on the scalp as small, round lumps. They can become tender if inflamed or infected.
  • Ingrown Hair (Pseudofolliculitis): This condition occurs when hair curls back into the skin, causing inflammation and potentially leading to a small, tender lump, especially in areas with curly hair.

Do Not Miss Diagnoses

  • Malignant Tumor (e.g., Basal Cell Carcinoma, Squamous Cell Carcinoma): Although less common, it's crucial to consider the possibility of skin cancer, especially if the lump is growing, bleeding, or has an unusual appearance. Early detection is key to effective treatment.
  • Infected Cyst or Abscess: An infected cyst or abscess on the scalp can present as a tender lump. If left untreated, it could lead to more serious infections, including those that spread beyond the scalp.

Rare Diagnoses

  • Keratoacanthoma: A rare, low-grade malignancy that can appear as a small, round, flesh-colored lump on the scalp. It often grows quickly but can regress on its own.
  • Dermatofibroma: A benign skin growth that can appear as a small, round lump, often following minor injury, and can be tender to the touch.
  • Trichoepithelioma: A rare, benign tumor of the hair follicle that can present as a small, round lump on the scalp.

Each of these diagnoses should be considered based on the clinical presentation, patient history, and further diagnostic tests if necessary.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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