Differential Diagnosis for Swelling of the Skin along the Glans Penis
Single Most Likely Diagnosis
- Contact Dermatitis: This is a common condition that can cause swelling, redness, and itching of the skin after coming into contact with an irritant or allergen. Given the localized nature of the symptoms to the glans penis, it's plausible that exposure to a new soap, condom, or other product could be the culprit.
Other Likely Diagnoses
- Balanitis: An inflammation of the glans penis, often caused by poor hygiene, infections (bacterial, fungal, or viral), or an allergic reaction. It can present with swelling, redness, and sometimes discharge.
- Phimosis: A condition where the foreskin cannot be fully retracted over the glans penis. It can lead to swelling due to the accumulation of smegma or other debris under the foreskin, which may cause irritation and inflammation.
- Urethritis: Inflammation of the urethra, which can be caused by infection (commonly sexually transmitted infections like gonorrhea or chlamydia) or other irritants. While it primarily affects the urethra, it can cause swelling around the urethral opening on the glans penis.
Do Not Miss Diagnoses
- Penile Cancer: Although rare, penile cancer can present with a variety of symptoms including swelling, especially if the cancer involves the glans penis. Early detection is crucial for effective treatment.
- Necrotizing Fasciitis: A severe infection that destroys tissue under the skin, including fat and the tissue covering the muscles (fascia). It's a medical emergency that requires immediate attention.
- Fournier's Gangrene: A type of necrotizing fasciitis that affects the genital area, characterized by severe pain, swelling, and potentially life-threatening complications if not promptly treated.
Rare Diagnoses
- Melanoma or Other Skin Cancers: While more commonly associated with sun-exposed areas, melanoma and other skin cancers can occur on the penis, including the glans. They might present as unusual growths or changes in pigmentation.
- Sarcoidosis: A condition that can cause inflammation in various parts of the body, including the skin. It might lead to swelling and lesions on the glans penis, though this is uncommon.
- Lymphedema: Swelling caused by impaired lymph drainage. It's rare for lymphedema to be localized to the glans penis but could occur in the context of more widespread lymphatic dysfunction or after surgical removal of lymph nodes.