Can missing a Slynd (drospirenone) pill cause overheating?

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Missing a Slynd Pill and Overheating

Missing a Slynd (drospirenone) pill is not directly associated with overheating symptoms the next evening or morning.

Understanding Slynd and Missed Pills

Slynd is a drospirenone-only pill, which is a newer progestin-only contraceptive that provides more flexibility for delayed or missed pills while maintaining efficacy compared to other progestin-only pills 1.

When a progestin-only pill like Slynd is missed, the CDC guidelines recommend the following actions:

  • Take one pill as soon as possible
  • Continue taking pills daily at the usual time (even if it means taking two pills on the same day)
  • Use backup contraception for 2 consecutive days
  • Consider emergency contraception if you've had unprotected intercourse 2

Drospirenone and Body Temperature

Drospirenone has unique properties compared to other progestins:

  • It has antimineralocorticoid activity similar to natural progesterone 3
  • It can cause mild natriuresis (increased sodium excretion) 4
  • It may counteract fluid retention that is sometimes associated with other hormonal contraceptives 3

While some drugs can affect thermoregulation and body temperature 5, there is no evidence in the medical literature specifically linking missed drospirenone pills to overheating symptoms.

What Happens When You Miss a Pill

When you miss a progestin-only pill like Slynd, the primary concerns are:

  1. Reduced contraceptive efficacy
  2. Potential for breakthrough bleeding
  3. Need for backup contraception

The CDC defines a missed progestin-only pill as one taken more than 3 hours past the recommended dose time 2. However, Slynd has a longer window (up to 24 hours) before being considered "missed" due to its unique formulation 1.

Common Side Effects vs. Overheating

Common side effects of hormonal contraceptives may include:

  • Cycle irregularity
  • Headache
  • Nausea
  • Breast tenderness

However, overheating is not listed as a typical side effect of missed hormonal contraceptive pills 2.

Important Considerations

  • If you're experiencing overheating symptoms after missing a pill, it may be coincidental or related to other factors
  • If overheating is severe or persistent, consult your healthcare provider as it could be related to another medical condition
  • Always follow the instructions for missed pills to maintain contraceptive effectiveness

Conclusion

Based on the available medical evidence, missing a Slynd pill would not be expected to cause overheating symptoms the next day. If you're experiencing such symptoms, consider other potential causes and consult with your healthcare provider if the symptoms persist or are severe.

References

Research

New Contraception Update - Annovera, Phexxi, Slynd, and Twirla.

Current obstetrics and gynecology reports, 2022

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Antimineralocorticoid activity of a novel oral contraceptive containing drospirenone, a unique progestogen resembling natural progesterone.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2002

Research

The effects of drugs on thermoregulation.

AACN clinical issues, 2004

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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