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Last updated: July 22, 2025View editorial policy

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Differential Diagnosis for Upper Abdominal Pain after Orthopedic Surgery

Single Most Likely Diagnosis

  • Postoperative ileus: This condition is a common cause of upper abdominal pain after surgery, including orthopedic procedures. It involves a temporary paralysis of the intestinal muscles, leading to a buildup of food, fluids, and gas, causing discomfort and pain.

Other Likely Diagnoses

  • Gastroesophageal reflux disease (GERD): Increased intra-abdominal pressure from surgery or immobility can exacerbate GERD symptoms, leading to upper abdominal pain.
  • Constipation: Postoperative constipation is common due to pain medications, immobility, and changes in diet, which can cause abdominal pain.
  • Musculoskeletal pain: Direct trauma or strain to the abdominal muscles during surgery can cause pain, as can the positioning on the operating table.

Do Not Miss Diagnoses

  • Pulmonary embolism: Although it primarily presents with respiratory symptoms, pulmonary embolism can sometimes cause upper abdominal pain, especially if it leads to right ventricular strain affecting liver capsule stretching.
  • Myocardial infarction: Cardiac events can manifest as upper abdominal pain, especially in women, diabetics, or the elderly, due to referred pain.
  • Peptic ulcer disease: Stress from surgery can lead to the development or exacerbation of peptic ulcers, causing severe abdominal pain.
  • Hepatic or splenic injury: Rare but possible, especially if the patient experienced trauma or had a complicated surgical procedure.

Rare Diagnoses

  • Pancreatitis: Can be triggered by various factors including certain medications, gallstones, or direct trauma during surgery.
  • Cholecystitis: Inflammation of the gallbladder, which could be precipitated by the surgical stress response or immobility leading to gallstone formation.
  • Hepatic vein thrombosis: A rare condition that could occur in the postoperative period, especially in patients with hypercoagulable states.
  • Abdominal compartment syndrome: A life-threatening condition that can occur after significant trauma or surgery, leading to increased pressure within the abdominal cavity.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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