Differential Diagnosis for Multiple Bullae on Feet
- Single most likely diagnosis
- Contact dermatitis: This is a common condition that can cause bullae on the feet due to irritation from shoes, socks, or other external factors. The presence of multiple bullae in this area suggests a reaction to an allergen or irritant.
- Other Likely diagnoses
- Dyshidrotic eczema: Characterized by small, itchy blisters on the hands and feet, dyshidrotic eczema is a possible cause of multiple bullae on the feet.
- Pompholyx: A type of eczema that affects the hands and feet, pompholyx can cause bullae and is often associated with excessive sweating.
- Bullous impetigo: A bacterial infection that can cause bullae on the skin, bullous impetigo is a possible diagnosis, especially if the bullae are filled with a cloudy or purulent fluid.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Stevens-Johnson syndrome: A severe skin and mucous membrane disorder, Stevens-Johnson syndrome can cause bullae and is often associated with medication use or infection. It requires prompt recognition and treatment to prevent serious complications.
- Toxic epidermal necrolysis: A life-threatening condition that causes widespread skin necrosis and bullae, toxic epidermal necrolysis is a medical emergency that requires immediate attention.
- Autoimmune bullous disorders (e.g., pemphigus, pemphigoid): These conditions can cause bullae and are often associated with significant morbidity and mortality if left untreated.
- Rare diagnoses
- Epidermolysis bullosa: A group of genetic disorders that cause blistering of the skin, epidermolysis bullosa is a rare condition that can present with bullae on the feet.
- Bullous systemic lupus erythematosus: A rare manifestation of systemic lupus erythematosus, bullous systemic lupus erythematosus can cause bullae on the skin, including the feet.