From the Research
Medical Significance of Pentadeca Arginate
The medical significance of Pentadeca arginate, potentially related to arginine, can be understood through its effects on various physiological processes.
- The study 1 investigated the influence of a novel pentadecapeptide, BPC 157, on N(G)-nitro-L-arginine methylester and L-arginine effects on stomach mucosa integrity and blood pressure, suggesting that BPC 157 could interfere with the effects of NO on both gastric mucosal integrity and blood pressure maintenance in a specific way, especially with L-arginine.
- Another study 2 found that BPC 157 reduced bleeding and thrombocytopenia after amputation in rats treated with heparin, warfarin, L-NAME, and L-arginine, implying a modulatory and balancing role of BPC 157 with rescued NO-hemostatic mechanisms.
- However, other studies 3, 4, 5 do not provide direct evidence related to Pentadeca arginate and its medical significance in relation to arginine.
Relation to Arginine
The relationship between Pentadeca arginate and arginine is primarily explored in the context of BPC 157, a pentadecapeptide.
- The study 1 compared the effects of BPC 157 and L-arginine on gastric mucosa integrity and blood pressure, indicating that BPC 157 had a more prominent and/or particularly different effect from that of NO.
- The study 2 also investigated the effects of L-NAME and L-arginine on hemostatic parameters and the effects of BPC 157 on the L-NAME- and L-arginine-induced hemostatic actions, suggesting that BPC 157 counteracted the effects of L-NAME and L-arginine on bleeding and thrombocytopenia.