What is the proper procedure for preparing a patient for intubation?

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Last updated: July 23, 2025View editorial policy

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Proper Procedure for Patient Intubation Preparation

Proper patient preparation for intubation requires a systematic approach including positioning, preoxygenation, monitoring, and medication administration to minimize complications and maximize success. 1

Initial Assessment and Preparation

Airway Assessment

  • Use MACOCHA score to predict difficult intubation (scores ≥3 indicate higher risk) 1
    • Mallampati class III or IV (5 points)
    • Obstructive sleep apnea (2 points)
    • Reduced cervical spine mobility (1 point)
    • Limited mouth opening <3 cm (1 point)
    • Coma (1 point)
    • Severe hypoxemia (SpO2 <80%) (1 point)
    • Non-anesthetist operator (1 point)

Team Assembly and Equipment

  • Assign clear roles to team members
  • Conduct pre-intubation checklist
  • Prepare and check all equipment:
    • Laryngoscope (with backup)
    • Appropriately sized endotracheal tubes
    • Suction device
    • Bag-valve-mask with PEEP valve
    • Capnography
    • Rescue devices (supraglottic airway, bougie)
    • Emergency front-of-neck access equipment

Patient Positioning

  • Position patient with head elevated 25-30° when tolerated
  • Use "sniffing position" (flex lower cervical spine, extend upper cervical spine)
  • For obese patients, use "ramping" (external auditory meatus level with sternal notch)
  • Ensure bed mattress is firm to optimize cricoid pressure application and access to cricothyroid membrane 1

Monitoring

  • Apply standard monitoring before induction:
    • Pulse oximetry
    • Waveform capnography
    • Blood pressure
    • Heart rate
    • ECG
    • End-tidal oxygen concentration (when available) 1

Preoxygenation

For Non-Hypoxemic Patients

  • Use tight-fitting facemask with 10-15 L/min of 100% oxygen for 3 minutes
  • Target end-tidal oxygen concentration >85%
  • Use two-handed technique to minimize mask leak
  • Do not use standard Hudson-type masks for preoxygenation 1

For Hypoxemic Patients

  • Consider CPAP (5-10 cmH2O) with NIV
  • Use supported breaths (tidal volume 7-10 mL/kg)
  • Consider high-flow nasal oxygen (HFNO) at 30-70 L/min
  • For agitated patients, consider delayed sequence induction with small doses of ketamine to facilitate preoxygenation 1

Hemodynamic Optimization

  • Include cardiovascular component in intubation protocol
  • Consider fluid challenge before induction in hypovolemic patients
  • Prepare vasopressors for early administration to prevent post-induction hypotension 1

Medication Administration

Induction Agents

  • Select appropriate hypnotic agent based on patient's hemodynamic status
  • Consider propofol, etomidate, or ketamine depending on clinical scenario 1

Neuromuscular Blocking Agents

  • Rocuronium: 0.6 mg/kg is the recommended initial dose for routine intubation
    • Provides intubation conditions within 1-2 minutes
    • Clinical relaxation for approximately 31 minutes
  • For rapid sequence intubation: 0.6-1.2 mg/kg rocuronium provides excellent intubation conditions within 2 minutes 2

Post-Intubation Care

  • Apply PEEP of at least 5 cmH2O after intubation in hypoxemic patients
  • Consider recruitment maneuver in hypoxemic patients
  • Confirm tube placement with waveform capnography
  • Secure the tube properly 1

Special Considerations

Obese Patients

  • Dose rocuronium based on actual body weight, not ideal body weight 2
  • Preoxygenation is enhanced in seated position (25°) 3

Critically Ill Patients

  • Standard preoxygenation methods may be less effective 4
  • Consider combining HFNO and NIV for preoxygenation 1
  • Apply post-intubation recruitment maneuver 1

Aspiration Risk

  • Consider rapid sequence induction for patients with:
    • Full stomach (no 2h liquid/6h food fasting)
    • Active vomiting
    • Ileus or sub-ileus
    • Impaired protective reflexes
    • Pregnant women in 3rd trimester 5

Common Pitfalls and Caveats

  1. Inadequate preoxygenation: Ensure tight mask seal and confirm adequate preoxygenation with end-tidal oxygen measurement
  2. Failure to recognize difficult airway: Complete airway assessment even in emergency situations
  3. Hemodynamic collapse: Prepare vasopressors before induction
  4. Delayed recognition of esophageal intubation: Always confirm tube placement with waveform capnography
  5. Extending preoxygenation beyond 8 minutes: May be counterproductive in critically ill patients 6

By following this systematic approach to patient preparation for intubation, you can minimize complications and maximize success rates, ultimately improving patient outcomes in terms of morbidity and mortality.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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