From the Guidelines
Ortho-Novum, which contains Norethindrone and Ethinyl Estradiol, is primarily used as a combined oral contraceptive pill (COC) for birth control in adolescents and adults. The medication is a form of hormonal contraception that contains both a progestin (Norethindrone) and an estrogen (Ethinyl Estradiol) component, which work together to prevent ovulation and thus pregnancy 1.
Key Points About Ortho-Novum Use
- It is recommended to start with a COC containing 30 to 35 μg of ethinyl estradiol and a progestin like levonorgestrel or norgestimate, but any "low-dose" pill (containing ethinyl estradiol 35 μg or less) can be used 1.
- No gynecologic examination is needed to determine eligibility for COC use, but patients should be counseled on the importance of using a backup method for at least the first 7 days and the need for ongoing protection against STIs 1.
- Ortho-Novum has few contraindications in healthy female adolescents, but it should not be prescribed for patients with severe and uncontrolled hypertension, ongoing hepatic dysfunction, or other specific health conditions 1.
- The most serious adverse event associated with COC use is the increased risk of blood clots, but the risk is still lower than that associated with pregnancy and postpartum 1.
Managing Adverse Effects and Interactions
- Common transient adverse effects of COCs include irregular bleeding, headache, and nausea, and recommendations for managing these effects are available 1.
- Drug interactions should be avoided, particularly with medications that decrease COC effectiveness, such as anticonvulsants and antiretroviral drugs 1.
- Patients should be instructed on what to do if pills are missed and reminded that 7 consecutive hormone pills are needed to prevent ovulation 1.
Additional Considerations
- Extended or continuous cycles of COC use may be useful for treating certain medical conditions, such as anemia, acne, and dysmenorrhea, and for adolescents who prefer amenorrhea 1.
- Observational data indicate that COC use does not increase the risk of infertility or breast cancer and provides significant protection against endometrial and ovarian cancers 1.
From the Research
Ortho-Novum (Norethindrone and Ethinyl Estradiol) Usage
There are no research papers provided to assist in answering this question about Ortho-Novum (Norethindrone and Ethinyl Estradiol). The studies cited 2, 3, 4, 5, 6 discuss the treatment of attention deficit hyperactivity disorder (ADHD) and the use of stimulant medications, but do not mention Ortho-Novum or its components.
- The provided studies focus on ADHD treatment options, including stimulants and non-stimulants.
- They discuss the efficacy and safety of various medications, such as methylphenidate, amphetamine, and atomoxetine.
- None of the studies mention Ortho-Novum or its use for any medical condition.