Ketorolac IM Packaging
Ketorolac for intramuscular (IM) administration is available in single-dose vials and ampules, with ampules being the more common packaging format.
Packaging Information
Ketorolac tromethamine for IM injection is typically supplied in:
- Single-dose glass ampules (most common)
- Single-dose vials (less common)
The packaging format may vary by manufacturer and country, but both delivery systems contain the same medication for intramuscular administration.
Dosage Information
When administering ketorolac IM, it's important to be aware of the proper dosing:
- Standard IM dose: 60 mg IM every 15-30 minutes as needed 1
- Maximum daily dosage: 120 mg per day 1
- Maximum duration: Treatment should not exceed 5 days 1
Administration Considerations
Proper Technique
- Administer into large muscle mass (gluteal or lateral thigh preferred)
- Use appropriate needle length to ensure intramuscular delivery
- Avoid inadvertent intravascular injection
Important Precautions
- Contraindicated in patients with:
- Aspirin/NSAID-induced asthma
- Pregnancy
- Cerebrovascular hemorrhage 1
- Bleeding disorders
Common Adverse Effects
- Edema
- Drowsiness
- Dizziness
- GI upset
- Increased diaphoresis 1
Clinical Pearls
Avoid Splitting Doses: When using ampules, the entire contents should be used for a single dose. Partial use of an ampule is not recommended due to sterility concerns.
Storage Requirements: Both ampules and vials should be stored at controlled room temperature (20-25°C/68-77°F).
Inspection Before Use: Solution should be clear; discard if particulate matter or discoloration is observed.
Compatibility: Do not mix with other medications in the same syringe.
Transition to Oral Therapy: For ongoing pain management beyond initial IM dosing, transition to oral ketorolac or other oral NSAIDs when possible to minimize injection-related risks.
Remember that ketorolac IM is intended for short-term management of moderate to severe acute pain and should be used at the lowest effective dose for the shortest duration possible to minimize adverse effects.