Treatment of Large Bite Wounds
For large bite wounds, immediate and thorough irrigation with copious amounts of warm or room temperature potable water is the most effective first-line treatment to prevent infection and promote healing. 1
Initial Management
Wound Cleansing:
Wound Assessment:
- Evaluate depth, location, and structures potentially involved
- Check for signs of infection (redness, swelling, warmth, pain)
- Determine if the bite is from a human or animal (treatment approach varies)
Treatment Algorithm
For All Large Bite Wounds:
Clean thoroughly:
- Irrigate with water or saline solution
- Consider using a virucidal agent such as povidone-iodine solution for additional cleansing 1
Cover appropriately:
- Apply antibiotic ointment or cream
- Use a clean occlusive dressing to cover the wound 1
Elevate the affected area if swollen to accelerate healing 1
For Animal Bites:
Consider rabies risk:
- Identify the animal if possible
- Contact local health department for guidance on rabies prophylaxis 1
- High-risk animals include bats, raccoons, skunks, foxes, and unvaccinated dogs/cats
Wound closure considerations:
For Human Bites:
Higher infection risk:
Special attention to hand wounds:
- Hand bites require expert evaluation for potential penetration into joints, tendons, or bone 1
- These wounds generally should not be closed
When to Seek Medical Attention
Seek immediate medical care for:
- Deep puncture wounds
- Bites to the face, hands, feet, or joints
- Signs of infection (increasing redness, swelling, pain)
- Bites from wild or unknown animals
- Human bites that break the skin
Common Pitfalls to Avoid
Do not apply:
Do not close large bite wounds without proper cleaning and medical evaluation 1
Do not delay treatment - immediate wound cleansing significantly reduces infection risk 1
Special Considerations
- Tetanus prophylaxis: Ensure tetanus vaccination is current; if outdated or unknown, administer tetanus toxoid 1
- Antibiotic prophylaxis: May be necessary for high-risk bites (human bites, deep punctures, hand injuries) 1
- Monitoring: Watch for signs of infection for at least 48 hours after the bite
By following these guidelines, you can significantly reduce the risk of infection and complications from large bite wounds. The most critical step remains immediate and thorough irrigation with water, which has the strongest evidence base for preventing infection.