What are the current mortality rates from Coronavirus Disease 2019 (COVID-19) worldwide and in the United States of America (USA)?

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Last updated: March 4, 2025View editorial policy

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From the Guidelines

As of the most recent update, the global death toll from COVID-19 was approximately 6.6 million people, with over 600 million infections reported worldwide, as of November 25,2022, according to the study published in the Journal of Microbiology, Immunology and Infection 1. The mortality rates from Coronavirus Disease 2019 (COVID-19) worldwide and in the United States of America (USA) are significant, with the global death toll likely being underestimated due to inconsistent reporting methods and limited testing capacity in many regions.

  • The actual numbers are probably higher, with some experts suggesting the global death toll could be more than twice the officially reported figure.
  • Death rates have varied significantly across countries and time periods, influenced by factors such as population demographics, healthcare system capacity, vaccination rates, and implementation of public health measures.
  • The study published in the Journal of Microbiology, Immunology and Infection 1 provides the most recent and reliable estimate of the global death toll from COVID-19, with over 6.6 million deaths reported as of November 25,2022.
  • It is essential to note that these numbers continue to change as the pandemic evolves, and for the most current statistics, I recommend checking reliable sources like the World Health Organization, Johns Hopkins University's COVID-19 dashboard, or your national public health agency.
  • The other studies, such as the ones published in the International Journal of Nursing Studies 1 and the European Respiratory Journal 1, provide valuable information on the management of COVID-19 and its impact on specific populations, but they do not provide more recent or accurate estimates of the global death toll.

From the Research

Global Mortality Rates

  • The World Health Organization estimates that there were 14.83 million excess deaths globally due to the COVID-19 pandemic, which is 2.74 times more deaths than the 5.42 million reported as due to COVID-19 for the period 2.
  • A systematic analysis of COVID-19-related mortality estimated that 18.2 million people died worldwide because of the COVID-19 pandemic, as measured by excess mortality, between January 1,2020, and December 31,2021 3.
  • The global all-age rate of excess mortality due to the COVID-19 pandemic was 120.3 deaths per 100,000 of the population 3.

Mortality Rates in the United States of America (USA)

  • The estimated number of excess deaths due to COVID-19 in the USA was 1.13 million, with an excess mortality rate of 179.3 deaths per 100,000 population 3.
  • The USA had one of the highest numbers of cumulative excess deaths due to COVID-19, along with countries such as India, Russia, Mexico, Brazil, Indonesia, and Pakistan 3.

Regional Variations in Mortality Rates

  • There were wide variations in the excess death estimates across the six World Health Organization regions, with the highest numbers of excess deaths in the regions of south Asia, north Africa and the Middle East, and eastern Europe 2, 3.
  • Some countries, such as Peru, Ecuador, Bolivia, and Mexico, had excess mortality rates above 50% of the expected annual mortality or above 400 excess deaths per 100,000 population 4.
  • In contrast, some countries, such as Australia and New Zealand, had mortality during the pandemic below the usual level, presumably due to social distancing measures decreasing non-COVID infectious mortality 4.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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