What is the best approach to managing hand deformity caused by Osteoarthritis (OA) of the thumb?

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Last updated: July 24, 2025View editorial policy

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Management of Hand Deformity Caused by Thumb Osteoarthritis

For patients with hand deformity caused by thumb osteoarthritis, a comprehensive treatment approach should begin with non-surgical interventions including orthoses (splints), exercises, and topical NSAIDs, with surgery (specifically trapeziectomy) reserved for cases with severe symptoms that fail to respond to conservative management.

Non-Surgical Management Options

Orthoses (Splints)

  • Orthoses should be considered first-line treatment for symptom relief in patients with thumb base OA 1
  • Long-term use (minimum 3 months) is strongly advocated for optimal outcomes 1, 2
  • Custom-made orthoses are preferred over prefabricated ones to improve patient compliance 2
  • Evidence shows orthoses effectively reduce pain without negative effects on function, strength, or dexterity 3

Exercise Therapy

  • Exercises to improve function and muscle strength should be considered for every patient 1
  • Focus should include:
    • Range of motion exercises
    • Strengthening exercises for intrinsic and extrinsic finger muscles
    • Joint mobilization techniques 2
  • Manual therapy combined with therapeutic exercise has shown moderate quality evidence for improving pain in thumb CMC OA at short- and intermediate-term follow-up 4

Pharmacological Management

  • Topical treatments are preferred over systemic treatments due to safety considerations 1
  • Treatment algorithm:
    1. First-line: Topical NSAIDs (particularly diclofenac gel) 1, 2
    2. Second-line: Oral paracetamol (up to 4g/day) 1
    3. Third-line: Oral NSAIDs at lowest effective dose and shortest duration if inadequate response to paracetamol 1
    4. Consider: Chondroitin sulfate for pain relief and functional improvement 1

Intra-articular Injections

  • Intra-articular corticosteroid injections may provide short-term pain relief for painful flares of thumb base OA 1
  • However, current guidelines suggest these should not generally be used in hand OA except in specific cases of painful interphalangeal joints 1
  • Evidence suggests hyaluronate injections may be more effective than steroid injections, though follow-up studies are generally short-term (maximum 12 months) 3

Surgical Management

  • Surgery should be considered only when other treatment modalities have not been sufficiently effective in relieving pain 1
  • Trapeziectomy is the recommended surgical procedure for patients with thumb base OA 1
  • Simpler surgical procedures (like trapeziectomy alone) are preferable to combination procedures, as they have similar efficacy with fewer complications 1
  • The Cochrane Musculoskeletal Group review found that combination surgical procedures (e.g., trapeziectomy + ligament reconstruction) offered no advantage over single procedures but had higher complication rates 1

Monitoring and Follow-up

  • Regular assessment of treatment response should be conducted, with evaluation of:
    • Range of motion
    • Pain levels
    • Functional improvement
    • Ability to perform activities of daily living 2
  • Consider discussing surgical options if no clinically relevant improvement is seen after 6 weeks of therapy, as 73-83% of patients who don't improve by 6 weeks also show no improvement at 3 months 5

Important Considerations

  • Patients with either high pain or low function may benefit most from conservative treatment, so it's recommended to always start with non-surgical approaches regardless of symptom severity 5
  • Education on joint protection principles, ergonomics, and pacing of activity should be offered to every patient 1
  • A dynamic stability model approach (including proprioceptive exercises and neuromuscular re-education) shows promising results for thumb CMC OA management 6
  • Disease-modifying OA drugs (DMOADs) for hand OA are currently not available 7

By following this structured approach to managing thumb OA-related hand deformity, clinicians can optimize outcomes while minimizing risks, with the ultimate goal of controlling symptoms and maximizing hand function, activity, participation, and quality of life.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Stable Flexion Deformity at the PIP Joint

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Dynamic stabilization of the painful thumb: A historical and evidence-informed synthesis.

Journal of hand therapy : official journal of the American Society of Hand Therapists, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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