From the Guidelines

Yes, a polyphenols and chlorogenic acid (CGA) formulation is available.

Polyphenols, including chlorogenic acid, are found in various plant-based foods and beverages, such as green coffee, tea, and certain fruits and vegetables 1.
Chlorogenic acid, in particular, has been shown to have anti-AGE activity and is found in high amounts in green coffee and some herbal teas 1.
Various studies have demonstrated the potential health benefits of polyphenol-rich formulations, including reducing the risk of chronic diseases such as cardiovascular disease and certain cancers 1.
Some food supplements and functional foods, such as those containing grape skin extracts or olive mill wastewater, have been shown to have anti-glycative properties and may be useful in reducing dietary AGE intake 1.
Encapsulation of polyphenolic compounds, such as quercetin, may be a promising strategy to protect these compounds from degradation during digestion and enhance their bioavailability 1.
Reformulation of foods to reduce sugar and fat content, and the addition of inhibitors from food by-products, may be another strategy to achieve sustainable health and reduce dietary AGE intake 1.

From the Research

There is evidence to suggest that CGA is widely available in plant foods, including green coffee beans, teas, certain fruits, and vegetables 2, 3, 4.
CGA is a naturally occurring non-flavonoid polyphenol that can be found in various commercial products, such as coffee and herbal infusions 5, 6.
The estimated dietary intake of CGA is 5 to 1000 mg/d, with daily oral doses of 13.5mg to 1200 mg showing potential health benefits 2.
CGA has been reported to have various health benefits, including antioxidant, anti-inflammatory, antibacterial, and antiviral effects 3, 4, 6.
However, there is no specific information available on a polyphenols and CGA formulation that is commercially available.

CGA has been shown to play a role in regulating glucose and lipid metabolism, improving insulin resistance, and reducing the risk of type 2 diabetes and cardiovascular diseases 2, 4.
CGA may also have anti-obesity properties, with potential benefits for weight management and blood pressure control 4.
The antioxidant and anti-inflammatory effects of CGA may help mitigate oxidative stress and related adverse effects associated with an unbalanced intracellular redox state 3, 6.

Green coffee beans are a rich source of CGA, with minor quantities also found in apples, eggplant, blueberries, tomatoes, strawberries, and potatoes 4.
Commercially available coffees, including ground and instant coffees, contain varying levels of CGA, with 5-CQA present at the highest levels 5.
Other food sources of CGA include teas, herbal infusions, and certain fruit juices, which may contribute to the estimated dietary intake of CGA 2, 6.