Morton's Neuroma: This condition is characterized by the thickening of the tissue around the nerves leading to the toes, causing numbness, pain, and puffiness in the ball of the foot. It is a common issue, especially among individuals who wear tight or high-heeled shoes.

Metatarsalgia: This refers to pain and inflammation in the ball of the foot, which can also lead to numbness and puffiness due to the pressure on the metatarsal bones.
Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion the joints can cause puffiness and numbness, especially if the bursae in the ball of the foot are affected.
Overuse or Repetitive Strain Injury: Activities that involve repetitive stress on the foot, such as running or dancing, can lead to puffiness and numbness due to strain on the muscles and nerves.

Deep Vein Thrombosis (DVT): Although less common, DVT can cause swelling and numbness in the foot. It is a serious condition that requires immediate medical attention to prevent pulmonary embolism.
Diabetic Neuropathy: For individuals with diabetes, high blood sugar levels can damage nerves, leading to numbness and other symptoms in the feet. Early detection is crucial to prevent further complications.
Infection (Cellulitis or Abscess): Bacterial infections can cause swelling, redness, and numbness. These conditions require prompt antibiotic treatment to prevent spread and serious complications.

Tarsal Tunnel Syndrome: Similar to carpal tunnel syndrome in the wrist, this condition involves compression of the posterior tibial nerve as it travels through the tarsal tunnel on the inner side of the ankle, leading to numbness and tingling in the foot.
Neurological Disorders (e.g., Peripheral Neuropathy): Certain conditions can cause widespread nerve damage, leading to numbness and other sensory changes in the feet.
Arthritis: While more commonly associated with joint pain, certain types of arthritis can cause swelling and numbness in the feet due to inflammation and nerve compression.