From the FDA Drug Label
The empirical formula for rosuvastatin calcium is (C 22H 27FN 3O 6S) 2Ca and the molecular weight is 1001. 14. Rosuvastatin tablets, USP for oral use contain rosuvastatin 5 mg, 10 mg, 20 mg, or 40 mg (equivalent to 5.2 mg, 10.4 mg, 20. 8 mg, and 41.6 mg rosuvastatin calcium, USP)
The calcium content in Rosuvastatin (Crestor) can be determined by the molecular formula of rosuvastatin calcium, which is (C 22H 27FN 3O 6S) 2Ca.
- The calcium component is represented by the "2Ca" in the molecular formula, indicating that two calcium ions are present for every two rosuvastatin molecules.
- The dosage forms contain rosuvastatin calcium, USP in the following amounts: 5.2 mg, 10.4 mg, 20.8 mg, and 41.6 mg. However, the exact calcium content in milligrams per tablet is not explicitly stated in the provided drug label 1.
From the Research
Rosuvastatin does not contain significant amounts of calcium that would contribute to dietary intake. Rosuvastatin is a prescription medication that belongs to a class of drugs called statins, which are used to lower cholesterol levels in the blood. It works by inhibiting an enzyme called HMG-CoA reductase, which plays a key role in cholesterol production in the liver. Unlike some other medications such as calcium supplements or calcium-containing antacids, rosuvastatin tablets do not contain calcium as an active or inactive ingredient that would provide a significant source of calcium. The active ingredient in rosuvastatin is rosuvastatin calcium, but this is a salt form of the drug and contributes negligible amounts of elemental calcium to your diet, as noted in various studies 2, 3, 4, 5, 6. If you are concerned about calcium intake for bone health or other reasons, you should discuss this with your healthcare provider, as rosuvastatin is not a source of dietary calcium. Some key points to consider about rosuvastatin include:
- Its high efficacy in improving lipid profiles 4, 5
- Its non-cholesterol-lowering actions, such as anti-inflammatory, antioxidant, and antithrombotic effects 6
- Its potential benefits in cardiovascular primary and secondary prevention 6 However, the primary consideration in this context is that rosuvastatin does not provide a significant source of calcium, and patients concerned about calcium intake should consult their healthcare provider.