From the Research
The best treatment for Parapsoriasis en plaques (PLEVA) typically involves phototherapy, particularly narrowband UVB, as it has been shown to be highly effective in managing symptoms and accelerating resolution, as seen in studies such as 1.
Treatment Options
- Topical corticosteroids, such as triamcinolone 0.1% or betamethasone 0.05%, can be used as first-line therapy for mild cases, applied twice daily to affected areas for 2-4 weeks.
- Oral antibiotics like erythromycin (500mg four times daily) or tetracycline (500mg twice daily) for 4-6 weeks may be effective for more severe cases due to their anti-inflammatory properties.
- Phototherapy, particularly narrowband UVB administered 2-3 times weekly for 6-10 weeks, is highly effective for widespread disease, as shown in studies such as 1.
- In resistant cases, methotrexate (7.5-25mg weekly) or immunosuppressants like cyclosporine may be necessary, as seen in cases such as 2.
Management and Prevention
- Patients should avoid triggers like infections and certain medications.
- Gentle skin care products should be used, and affected skin should be protected from sun exposure while undergoing treatment.
- Regular follow-up is important to monitor treatment response and adjust therapy as needed.
Disease Characteristics
- PLEVA is a self-limiting condition that typically resolves within months to years.
- Treatment focuses on symptom management and accelerating resolution.
- The condition can have a significant impact on quality of life, making effective treatment crucial, as highlighted in studies such as 3.