Differential Diagnosis for Rimming Redness, Burning in Eyes, No Itching or Drainage

• Single Most Likely Diagnosis
  • Dry eye syndrome: This condition is characterized by a lack of sufficient lubrication on the surface of the eye, leading to redness and burning sensations. The absence of itching or drainage supports this diagnosis, as dry eye syndrome typically does not present with these symptoms.
• Other Likely Diagnoses
  • Conjunctivitis (viral or chemical): Although the question specifies no itching or drainage, some forms of conjunctivitis, especially viral or chemical, can present with redness and burning without significant discharge or itching.
  • Irritant exposure (e.g., chemicals, smoke): Exposure to irritants can cause redness and burning in the eyes without necessarily leading to itching or drainage.
• Do Not Miss Diagnoses
  • Acute angle-closure glaucoma: This is a medical emergency that can present with redness and burning in the eyes, among other symptoms like severe eye pain and vision changes. It's crucial to rule out this condition due to its potential for permanent vision loss if not promptly treated.
  • Corneal ulcer: Although less common, a corneal ulcer can cause redness and burning. It's a serious condition that requires immediate medical attention to prevent complications like vision loss.
• Rare Diagnoses
  • Sjögren's syndrome: An autoimmune disorder that can lead to dry eyes (keratoconjunctivitis sicca) among other symptoms. It's less likely but should be considered in the differential diagnosis, especially if other systemic symptoms are present.
  • Thygeson's superficial punctate keratitis: A condition characterized by small, discrete lesions on the cornea, leading to eye redness and discomfort. It's relatively rare and might not always present with the classic symptoms described.