From the FDA Drug Label
2.1 Dosage Each dose of GARDASIL 9 is 0. 5-mL. Administer GARDASIL 9 as follows: Age RegimenSchedule
- If the second dose is administered earlier than 5 months after the first dose, administer a third dose at least 4 months after the second dose. 9 through 14 years 2-dose0, 6 to 12 months* 3-dose0, 2,6 months 15 through 45 years 3-dose0, 2,6 months
The recommended schedule for Gardasil administration in a 33-year-old individual is a 3-dose schedule with doses administered at 0,2, and 6 months 1.
From the Research
Gardasil 9 vaccination is recommended for adults up to age 45, including those who are 33 years old, with a standard schedule consisting of three doses: the initial dose, followed by a second dose 1-2 months later, and a third dose 6 months after the first dose. For adults who have not been previously vaccinated, completing all three doses is crucial for optimal protection against human papillomavirus (HPV) types that cause most cervical cancers, as well as other HPV-related cancers and genital warts 2. Even if an individual has been sexually active or previously exposed to some HPV types, vaccination can still provide protection against other types they haven't encountered. The vaccine is most effective when given before any HPV exposure, but can provide benefits at any age up to 45.
Some key points to consider:
- The vaccine protects against HPV types 6,11,16,18,31,33,45,52, and 58, which can cause various cancers and genital warts 3.
- Side effects are typically mild and may include pain at the injection site, headache, or fatigue.
- The vaccine is generally covered by insurance for adults through age 45, but it's essential to verify coverage with the provider.
- The Centers for Disease Control and Prevention (CDC) and other health organizations recommend HPV vaccination for all individuals through age 26, and shared clinical decision-making for those aged 27-45 who are not already vaccinated 4, 5.
It's also important to note that while there is evidence supporting the vaccination of individuals up to age 45, the primary focus of vaccination efforts remains on adolescents and young adults, as vaccination is most effective when administered before exposure to HPV 6. However, for a 33-year-old individual, following the recommended three-dose schedule of Gardasil 9 can provide significant protection against HPV-related diseases.