Should I take or skip a missed dose of Augmentin (amoxicillin/clavulanate) 875 if I am 6 hours late?

Missed Dose of Augmentin 875: Take It Late or Skip It?

You should take the missed dose of Augmentin 875 as soon as possible, even if you are 6 hours late, and then continue with your regular dosing schedule. This approach ensures you maintain adequate antibiotic levels in your system to effectively treat your infection.

Rationale for Taking the Late Dose

The FDA drug label for amoxicillin/clavulanate (Augmentin) specifically states that the medication should be "taken exactly as directed" and emphasizes that "skipping doses or not completing the full course of therapy may decrease the effectiveness of the immediate treatment and increase the likelihood that bacteria will develop resistance" 1.

Timing Considerations:

• 6 hours late is well within the acceptable window for taking a missed dose
• For most antibiotics, including Augmentin, maintaining consistent blood levels is crucial for efficacy

Decision Algorithm for Missed Antibiotic Doses

1. If less than halfway to next scheduled dose (as in your case - 6 hours late):

   • Take the missed dose immediately
   • Resume regular schedule for remaining doses
   • Do not double up on doses

2. If more than halfway to next scheduled dose:

   • Skip the missed dose
   • Take the next dose at the regularly scheduled time
   • Do not double up on doses

Importance of Completing the Full Course

Even if you're feeling better, completing the full prescribed course of Augmentin is critical because:

• Premature discontinuation can lead to treatment failure
• Incomplete treatment may promote antibiotic resistance
• The infection may recur if not fully eradicated

Common Pitfalls to Avoid

• Don't double up on doses to "catch up" - this can increase side effects without improving efficacy
• Don't extend your treatment beyond what was prescribed unless specifically instructed by your healthcare provider
• Don't save leftover antibiotics for future use - dispose of any remaining medication properly after completing the prescribed course

Side Effects to Be Aware Of

While taking your late dose, be mindful that Augmentin commonly causes:

• Gastrointestinal effects (diarrhea, nausea)
• Rash
• Yeast infections

If you experience severe diarrhea or other concerning symptoms, contact your healthcare provider.

Remember that completing your full course of antibiotics, even if doses are occasionally delayed, is essential for effective treatment of your infection and prevention of antibiotic resistance.