From the Research
Primary Hyperparathyroidism (PTH) does not typically cause hirsutism in women, as hirsutism is usually related to hormonal imbalances involving androgens rather than PTH. The primary causes of hirsutism include polycystic ovary syndrome (PCOS), congenital adrenal hyperplasia, certain medications, Cushing's syndrome, and tumors that produce androgens 1. PTH regulates calcium and phosphate metabolism in the body, and its primary effects are on bone, kidneys, and intestines to maintain proper calcium levels. While severe hyperparathyroidism can cause various symptoms like bone pain, kidney stones, fatigue, and depression, increased facial hair is not a recognized direct effect of elevated PTH.
Some of the key factors to consider in the evaluation of hirsutism include:
- The presence of excess hair growth in a male-like pattern
- The potential underlying causes of hirsutism, such as PCOS, congenital adrenal hyperplasia, and androgen-secreting tumors
- The importance of assessing androgen levels and other hormonal tests to determine the cause of hirsutism
- The various treatment options available, including hormonal suppression, peripheral androgen blockade, and mechanical/cosmetic amelioration of unwanted hairs 2, 3, 1
It is essential to note that the treatment of hirsutism often requires a multidisciplinary approach, and a variety of physical or pharmacologic modalities can be employed 1. The aims of medical therapy are suppression of excessive androgen production, inhibition of peripheral action of androgens, and treatment of patients at risk for metabolic disorders or reproductive cancers.
In terms of specific treatment options, oral contraceptive pills (OCPs) and antiandrogens, such as spironolactone, are commonly used to treat hirsutism 1. Additionally, physical modalities like electrolysis and laser hair removal can be effective in reducing excess hair growth.
Overall, while Primary Hyperparathyroidism (PTH) is not a typical cause of hirsutism in women, it is crucial to evaluate and treat hirsutism promptly to address the underlying hormonal imbalances and improve the patient's quality of life. Any woman experiencing excessive facial hair growth should consult with a healthcare provider for proper evaluation and treatment, which may involve a combination of medical and mechanical therapies 1.