Treatment of Arthropod Bites
The treatment of arthropod bites should focus on local wound care, symptomatic relief with antihistamines and topical corticosteroids, and immediate epinephrine administration for anaphylactic reactions. 1
Initial Assessment and Management
Non-Venomous Bites (Common Arthropod Bites)
Local Wound Care:
Symptomatic Relief:
Venomous Bites/Stings with Systemic Reactions
Emergency Treatment for Anaphylaxis:
- Administer epinephrine immediately for signs of anaphylaxis (difficulty breathing, tongue/throat swelling, lightheadedness, vomiting, disseminated hives) 1, 3
- Dosage: 0.01 mg/kg (up to 0.3 mg) in children and 0.3-0.5 mg in adults, intramuscularly 1
- Repeat dosing may be required for persistent symptoms 1
Supportive Care:
- Position patient appropriately
- Establish IV access
- Administer oxygen if needed
- Monitor vital signs 1
Treatment Based on Specific Arthropod Types
Spider Bites
Widow Spider (Latrodectus) Bites:
Brown Recluse (Loxosceles) Bites:
Hymenoptera Stings (Bees, Wasps, Hornets, Fire Ants)
Local reactions:
- Ice application
- Antihistamines
- Topical corticosteroids 4
Severe reactions:
- Epinephrine (as described above)
- Systemic glucocorticoids
- Antihistamines 4
Scorpion Stings
- Centruroides species (medically relevant in US):
- Analgesics
- Benzodiazepines
- Supportive care
- Antivenom in severe cases 4
Secondary Infection Management
If signs of infection develop:
- Consider antibiotic treatment with options including:
- Cephalexin (250 mg four times daily)
- Clindamycin (300-400 mg three times daily) for penicillin-allergic patients
- Amoxicillin-clavulanate (875/125 mg twice daily) 1
- Infected wounds should not be closed 2
Prevention of Future Bites
Repellents and Protective Measures:
Long-term Management for Those with Previous Reactions:
Follow-up Care
- Monitor for signs of secondary infection, systemic allergic reactions, and delayed healing 1
- Reevaluate in 48-72 hours if there is no improvement 1
- Ensure tetanus prophylaxis is current 2
Common Pitfalls and Caveats
- Delayed use of epinephrine in anaphylaxis can be ineffective or fatal 1
- Brown recluse spider bites are often overdiagnosed 4
- Tourniquets, suction, ice application, and electrical current are ineffective or potentially harmful for venomous snake bites and should be avoided 2
- Low-potency corticosteroids may not improve symptoms of arthropod bites 2