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Last updated: July 29, 2025View editorial policy

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Differential Diagnosis of Laryngeal Stridor

Single Most Likely Diagnosis

  • Laryngomalacia: This is the most common cause of laryngeal stridor, especially in infants. It is characterized by the softening of the tissues of the larynx, which can cause partial airway obstruction when inhaling.

Other Likely Diagnoses

  • Acute Epiglottitis: An inflammatory condition of the epiglottis that can cause stridor due to swelling and potential airway obstruction. It's more common in children but can occur in adults.
  • Croup: A common childhood condition characterized by a barking cough and stridor, usually resulting from a viral infection that causes inflammation of the larynx and trachea.
  • Foreign Body Aspiration: Objects lodged in the airway can cause stridor by physically obstructing airflow. This is a common emergency in children.
  • Laryngitis: Inflammation of the larynx, often due to viral infections, can lead to stridor, especially if there is significant swelling.

Do Not Miss Diagnoses

  • Anaphylaxis: A severe, life-threatening allergic reaction that can cause stridor due to swelling of the airway tissues. Prompt recognition and treatment are critical.
  • Angioedema: Similar to anaphylaxis, angioedema can cause rapid swelling of the airway, leading to stridor and potential airway obstruction.
  • Retropharyngeal Abscess: A bacterial infection that causes an abscess in the tissues at the back of the throat, which can push the airway forward and cause stridor.

Rare Diagnoses

  • Laryngeal Tumors: Though rare, especially in children, tumors of the larynx can cause stridor by obstructing the airway.
  • Subglottic Stenosis: A narrowing of the airway below the vocal cords, which can be congenital or acquired, leading to stridor.
  • Vocal Cord Paralysis: Unilateral or bilateral paralysis of the vocal cords can cause stridor, especially if the paralysis affects the ability of the cords to move apart during inhalation.
  • Tracheal Stenosis: Narrowing of the trachea, which can be congenital or acquired, leading to stridor and breathing difficulties.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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