What is the treatment for a simple cat scratch?

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Treatment for Simple Cat Scratch

For a simple cat scratch, immediate treatment involves thorough washing of the wound with soap and water. 1 This basic first aid measure is the most important step in preventing infection from a cat scratch.

Immediate Care for Cat Scratch

  • Wash the wound promptly and thoroughly with soap and water 2
  • Clean the area around the wound with an antiseptic solution
  • Apply an over-the-counter antibiotic ointment
  • Cover with a clean, dry bandage if needed

When to Seek Medical Attention

Most simple cat scratches heal without complications and don't require medical treatment. However, you should seek medical care if:

  • The wound appears deep or severely contaminated
  • Signs of infection develop (increasing redness, warmth, swelling, pain, or pus)
  • You develop fever or swollen lymph nodes
  • You are immunocompromised (HIV-infected, on immunosuppressive medications, etc.)
  • The scratch is on the face, hands, or near a joint

Special Considerations for High-Risk Individuals

Immunocompromised Patients

Immunocompromised individuals, particularly those with HIV infection and severe immunosuppression, should be especially cautious with cat scratches due to higher risk of developing Bartonella infection 2:

  • Consider the risks of cat ownership if severely immunosuppressed
  • If keeping cats, adopt animals older than 1 year in good health
  • Avoid rough play with cats
  • Implement flea control for cats
  • Seek prompt medical attention for any cat scratch

When Infection Develops (Cat Scratch Disease)

If infection develops (typically manifesting as tender lymphadenopathy), treatment options include:

  • Azithromycin is the first-line treatment for cat scratch disease (CSD), with dosage of 500 mg on day 1 followed by 250 mg for 4 additional days for patients >45 kg 1
  • For children <45 kg: 10 mg/kg on day 1 and 5 mg/kg for 4 more days 1
  • Alternative antibiotics include erythromycin, doxycycline, ciprofloxacin, or trimethoprim-sulfamethoxazole 3, 4

Prevention of Cat Scratches

  • Avoid rough play with cats 2
  • Don't allow cats to lick open wounds 1
  • Keep cats' nails trimmed
  • Implement proper flea control for cats 2
  • Supervise children's interactions with cats

Important Caveats

  • Most cases of simple cat scratches heal without complications and don't require antibiotic treatment 5
  • Cat scratch disease is more common in children but can affect adults as well 5
  • Immunocompromised individuals are at higher risk for developing more severe forms of Bartonella infection, including bacillary angiomatosis 6
  • Atypical presentations of cat scratch disease can include ocular involvement, encephalopathy, hepatitis, and other systemic manifestations 4

References

Guideline

Cat Scratch Disease Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Treatment of cat-scratch disease.

Current opinion in pediatrics, 2001

Research

Cat-scratch disease: epidemiology, aetiology and treatment.

British journal of biomedical science, 2001

Research

Cat-scratch Disease.

American family physician, 2011

Research

Cat-scratch disease and related clinical syndromes.

American family physician, 1997

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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