Immediate Management of Syncope and Collapse
The immediate management of syncope and collapse should focus on prompt recognition, high-quality CPR, and early defibrillator use if the patient remains unresponsive, as this represents a potential sudden cardiac arrest until proven otherwise. 1
Initial Assessment and Management Algorithm
Step 1: Assess Responsiveness and Vital Signs
- If patient is unresponsive → Presume sudden cardiac arrest until proven otherwise
- If patient has regained consciousness → Perform immediate vital sign assessment (BP, HR, RR, O2 saturation)
Step 2: For Unresponsive Patients
- Start high-quality CPR with minimal interruptions 1
- Attach defibrillator immediately (goal: first shock within 2 minutes if indicated) 1
- Continue CPR with effective rescue breaths according to resuscitation guidelines
- Consider advanced airway management if available (supraglottic airway)
- Attach supplemental oxygen when available
Step 3: For Responsive Patients
- Position patient supine with legs elevated if no trauma suspected
- Obtain IV access
- Perform 12-lead ECG immediately
- Check orthostatic vital signs when stable
- Assess for serious medical conditions requiring immediate intervention:
- Cardiac arrhythmias
- Acute coronary syndrome
- Pulmonary embolism (particularly in older patients) 2
- Aortic dissection
- Severe anemia/gastrointestinal bleeding
- Critical aortic stenosis
Risk Stratification for Hospital Admission
Hospital evaluation and treatment are recommended for patients with:
- Serious cardiac conditions (arrhythmias, structural heart disease)
- Abnormal ECG findings
- History of cardiac disease
- Age ≥50 years with concerning features
- Syncope during exertion
- Syncope without prodrome
- Family history of sudden cardiac death
- Evidence of acute bleeding 1
Patients with presumptive vasovagal syncope without serious medical conditions can typically be managed in outpatient settings 1.
Specific Management Based on Suspected Etiology
For Suspected Vasovagal Syncope
- Patient education on triggers and premonitory symptoms 1
- Teach counter-pressure maneuvers:
- Leg crossing with muscle tensing
- Hand gripping (squeezing a rubber ball)
- Arm tensing (isometric contraction) 1
- Ensure adequate hydration (2L fluid daily) and salt intake 1
- Consider midodrine for recurrent episodes (if no hypertension, heart failure, or urinary retention) 1
For Suspected Cardiac Syncope
- Continuous cardiac monitoring
- Urgent cardiology consultation
- Consider temporary pacing for bradyarrhythmias
- Antiarrhythmic medications for tachyarrhythmias as appropriate
For Suspected Orthostatic Syncope
- Volume repletion
- Review and modify medications that may contribute to hypotension
- Consider fludrocortisone for recurrent episodes (if no contraindications) 1
Common Pitfalls to Avoid
Failure to recognize cardiac syncope: Cardiac causes of syncope carry the highest mortality risk 3
Premature diagnosis of vasovagal syncope: Always exclude cardiac and neurological causes before attributing to vasovagal mechanism
Inadequate monitoring: Patients with unexplained syncope and cardiac risk factors require continuous monitoring
Overlooking pulmonary embolism: Syncope may be the presenting symptom of PE, especially in older patients 2
Inappropriate discharge: Patients with high-risk features should not be discharged without adequate evaluation
Moving collapsed athletes prematurely: In sports settings, assess and treat at the site of collapse unless immediate safety concerns exist 1
By following this structured approach to syncope management, clinicians can effectively identify high-risk patients requiring urgent intervention while appropriately managing those with benign causes, ultimately improving patient outcomes and reducing mortality.