What is the frequency of corpus callosotomy procedures in pediatric patients?

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From the Research

Frequency of Corpus Callosotomy Procedures in Pediatric Patients

  • The frequency of corpus callosotomy procedures in pediatric patients is not directly stated in the provided studies, but the studies suggest that it is a relatively rare procedure 1, 2, 3, 4, 5.
  • A study published in 2024 found that 83 patients underwent 85 corpus callosotomy procedures at 14 participating epilepsy centers 1.
  • Another study published in 2024 reported on a series of 10 consecutive pediatric patients who underwent MRI-guided stereotactic laser corpus callosotomy 2.
  • A study published in 2005 reported on a total of 257 pediatric patients who underwent epilepsy surgeries, with corpus callosotomy being one of the most common procedures 3.
  • A systematic review published in 2016 found 12 articles that met the inclusion criteria, with a total of 458 patients who underwent corpus callosotomy 4.
  • A study published in 2014 reported on a series of 58 children who underwent corpus callosotomy between 1995 and 2011 5.

Surgical Approaches and Outcomes

  • The studies suggest that different surgical approaches can be used for corpus callosotomy, including open craniotomy, laser interstitial thermal therapy, and mini-craniotomy/endoscopic approach 1, 2, 5.
  • The outcomes of corpus callosotomy procedures in pediatric patients are generally favorable, with significant reductions in seizure frequency and improvement in quality of life 1, 2, 3, 4, 5.
  • The choice of surgical approach may depend on various factors, including the severity of the epilepsy, the presence of other medical conditions, and the preferences of the patient and their family 1, 2, 5.

Complications and Risks

  • The studies suggest that corpus callosotomy procedures can be associated with complications and risks, including transient disconnection syndrome, neurological deficits, and operative complications 1, 2, 4, 5.
  • However, the overall risk of complications is generally considered to be low, and the benefits of the procedure often outweigh the risks 1, 2, 4, 5.

References

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