Which ophthalmological cases should be referred from Urgent Care (UC) to ophthalmology evaluation the same day?

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Ophthalmological Cases Requiring Same-Day Referral from Urgent Care to Ophthalmology

Urgent Care providers should immediately refer patients with retinal artery occlusions, posterior uveitis, severe visual impairment, or acute angle-closure glaucoma to ophthalmology for same-day evaluation to prevent permanent vision loss.

Vascular Emergencies

Retinal Artery Occlusions

  • Central Retinal Artery Occlusion (CRAO) or Branch Retinal Artery Occlusion (BRAO)
    • Patients presenting with sudden, painless vision loss should be treated as medical emergencies
    • These conditions represent ocular strokes and indicate high risk for cerebral stroke
    • Patients should be referred to both ophthalmology AND the nearest stroke center/emergency department 1
    • Up to 24% of these patients have concurrent cerebrovascular accidents on MRI 1
    • The risk of stroke is highest within the first 7 days and remains elevated for 30 days 1

Transient Monocular Vision Loss (TMVL)

  • Even if vision has returned to normal, these patients require urgent referral
  • May represent transient retinal ischemia (ocular TIA) and indicates stroke risk 1
  • Should be referred to both ophthalmology and a stroke center for evaluation

Inflammatory Conditions

Uveitis

  • Posterior or Pan-uveitis: Requires URGENT ophthalmology referral (preferably uveitis specialist) prior to initiating treatment 1
    • Unlike anterior uveitis, posterior uveitis can be asymptomatic but can rapidly progress to visual loss
    • Do not start corticosteroid treatment before ophthalmology evaluation as it may mask diagnosis or worsen conditions due to infection

Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis with Eye Involvement

  • Daily ophthalmological review is necessary during the acute illness 1
  • Apply ocular lubricants every 2 hours through the acute illness
  • Requires specialized ocular hygiene by an ophthalmologist or ophthalmically trained nurse

Acute Angle-Closure Glaucoma

  • Presents with eye pain, redness, blurred vision, halos around lights, headache, nausea, and vomiting 2, 3
  • Represents a true ophthalmological emergency with markedly elevated intraocular pressure
  • Can cause permanent vision damage if not treated promptly
  • Can sometimes present atypically with painless vision loss, mimicking other conditions 4
  • Patients on certain medications (sympathomimetics, anticholinergics, etc.) are at higher risk 5, 6

Severe Visual Impairment

  • Any patient with sudden blindness (20/200 or worse) in the affected eye 1
  • Marked decrease in visual acuity (worse than 20/40) with symptoms limiting self-care activities 1
  • Any acute, unexplained vision loss

Dupilumab-Related Ocular Surface Disorders (DROSD)

  • Severe DROSD: Requires ophthalmology assessment within 24 hours or urgent assessment within 1 week 1
  • Initiate preservative-free ocular lubricants while awaiting ophthalmology evaluation

Other Urgent Conditions

  • Suspected Giant Cell Arteritis: Patients with visual symptoms and elevated inflammatory markers should be seen immediately 1

    • Delaying glucocorticoid therapy when visual loss is present is the strongest risk factor for permanent blindness
  • Ocular chemical burns: Immediate irrigation and referral

  • Orbital cellulitis: Eyelid swelling with pain, erythema, proptosis, pain with eye movements, movement restriction/diplopia, vision changes 1

  • Penetrating eye injuries and ruptured globes

  • Retinal detachment symptoms: Sudden onset of floaters, flashes of light, or a curtain/shadow in visual field

Important Cautions

  • Do not start topical or systemic corticosteroids before ophthalmology evaluation for eye conditions, as this may mask diagnosis or worsen infectious conditions 1

  • For patients with retinal artery occlusions, coordinate care with both ophthalmology and stroke services, as these patients require evaluation for stroke and other cardiovascular risk factors 1

  • When in doubt about the urgency of an eye condition, err on the side of caution and refer for same-day evaluation

By following these guidelines, urgent care providers can help ensure that patients with vision-threatening conditions receive appropriate and timely care to preserve vision and prevent permanent visual impairment.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Acute Closed-Angle Glaucoma-an Ophthalmological Emergency.

Deutsches Arzteblatt international, 2021

Research

Drug-induced Acute Angle-closure Glaucoma: A Review.

Journal of current glaucoma practice, 2019

Research

Acute angle closure glaucoma - A potential blind spot in critical care.

Journal of the Intensive Care Society, 2017

Research

[Drug-induced acute angle closure glaucoma].

Revue medicale de Liege, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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