What is the treatment for a large hematoma?

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Treatment for Large Hematoma

The treatment for a large hematoma requires immediate control of bleeding points through direct pressure, tourniquets, or hemostatic dressings, followed by appropriate fluid resuscitation with warmed blood and blood components when necessary. 1

Initial Assessment and Management

Immediate Actions

  • Control obvious bleeding points using:
    • Direct pressure
    • Tourniquets (if appropriate)
    • Hemostatic dressings
  • Establish large-bore IV access (largest possible, including central access)
  • Obtain baseline blood tests:
    • Full blood count (FBC)
    • Prothrombin time (PT)
    • Activated partial thromboplastin time (aPTT)
    • Clauss fibrinogen
    • Cross-match
  • Perform rapid clinical assessment:
    • Look for injury patterns
    • Assess visible blood loss
    • Check for signs of internal bleeding
    • Evaluate vital signs (heart rate, blood pressure, capillary refill, skin color, consciousness) 1

Fluid Resuscitation

  • For massive hemorrhage, use warmed blood and blood components
  • Blood product administration priority:
    • Group O (quickest)
    • Group-specific
    • Cross-matched blood
  • Consider high-ratio transfusion strategy of 1:1:1 (plasma:platelets:PRBCs) for severely traumatized patients 2
  • Actively warm the patient and all transfused fluids 1

Diagnostic Imaging

  • Rapid access to imaging is essential:
    • Ultrasound
    • Radiography
    • CT scan (if patient is stable enough)
  • Use focused assessment with sonography for trauma (FAST) scanning when appropriate 1

Definitive Management

Surgical Intervention

  • Surgery must be considered early for large hematomas causing significant symptoms or complications
  • In some cases, "damage control" surgery may be necessary
  • For spinal epidural hematomas, decompressive laminectomy may be required in selected cases, though conservative management with factor replacement may be sufficient in certain patients 3
  • For intracerebral hematomas, stereotactic aspiration may be beneficial in selected cases 4

Non-surgical Management

  • Once bleeding is controlled:
    • Normalize blood pressure, acid-base status, and temperature
    • Avoid vasopressors
    • Provide active warming
    • Treat coagulopathy aggressively if present 1
  • Monitor for signs of rebleeding or hematoma expansion

Management of Coagulation Issues

  • Prevent dilutional coagulopathy with early infusion of fresh frozen plasma (FFP)
  • Target fibrinogen levels >1 g/L
  • Consider viscoelastic testing (TEG, ROTEM) for rapid evaluation of hemostasis
  • Maintain minimum platelet count of 75×10⁹/L 2

Post-Acute Care

  • Admit to critical care area for monitoring and observation
  • Monitor:
    • Coagulation parameters
    • Hemoglobin
    • Blood gases
    • Wound drains to identify ongoing bleeding 1
  • Initiate standard venous thromboprophylaxis as soon as bleeding is controlled, as patients rapidly develop a prothrombotic state 1, 2

Special Considerations

  • For patients with traumatic brain injury, maintain higher platelet transfusion threshold (100,000/mm³) 2
  • For subgaleal hematomas, complete surgical evacuation may be necessary in severe cases 5
  • For spinal hematomas, magnetic resonance imaging is the examination of choice, and early surgical decompression offers the best chance for complete recovery 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Massive Transfusion in Trauma Situations

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Spinal epidural hematoma in a hemophilic infant.

The American journal of pediatric hematology/oncology, 1993

Research

Massive subgaleal hematoma: a potentially fatal rare entity-a case-based review.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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