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Last updated: July 30, 2025View editorial policy

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Differential Diagnosis for Lesions in Eyebrow

  • Single most likely diagnosis
    • Seborrheic keratosis: This is a common, benign skin growth that can appear in the eyebrow area, often presenting as a small, dark, and slightly raised lesion.
  • Other Likely diagnoses
    • Basal cell carcinoma: A type of skin cancer that can occur in the eyebrow area, presenting as a small, shiny, or pink bump.
    • Squamous cell carcinoma: Another type of skin cancer that can appear in the eyebrow area, often as a firm, red nodule.
    • Melanocytic nevus (mole): A benign growth of pigment-producing cells that can appear in the eyebrow area.
    • Wart (verruca vulgaris): A viral infection that can cause a small, rough lesion in the eyebrow area.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Malignant melanoma: A highly aggressive and potentially deadly form of skin cancer that can appear in the eyebrow area, often presenting as a new or changing mole.
    • Merkel cell carcinoma: A rare and aggressive form of skin cancer that can appear in the eyebrow area, often as a firm, painless nodule.
  • Rare diagnoses
    • Trichoepithelioma: A rare, benign tumor of the hair follicle that can appear in the eyebrow area.
    • Pilomatrixoma: A rare, benign tumor of the hair follicle that can appear in the eyebrow area, often as a firm, blue-gray nodule.
    • Metastatic cancer: In rare cases, cancer from another part of the body can metastasize to the eyebrow area, presenting as a new or changing lesion.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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