What is the cause of a persistent left-sided headache for one week that is unresponsive to analgesics (pain relievers)?

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Differential Diagnosis for Left Side Headache

  • Single most likely diagnosis
    • Migraine: This is a common cause of unilateral headaches that can be severe and debilitating. The fact that it's not improving with analgesics could suggest a migraine, especially if the patient experiences other migraine symptoms like nausea, vomiting, or sensitivity to light and sound.
  • Other Likely diagnoses
    • Tension headache: Although typically bilateral, tension headaches can occasionally present unilaterally and may not respond immediately to over-the-counter analgesics.
    • Cluster headache: Known for severe, unilateral pain, often around the eye, cluster headaches can occur on one side of the head and may not respond well to conventional analgesics.
    • Sinusitis: If the headache is accompanied by facial pain, nasal congestion, or fever, sinusitis could be a likely cause, especially if the pain is localized to the left side of the face.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Subarachnoid hemorrhage: A sudden, severe headache (often described as "the worst headache of my life") could indicate a subarachnoid hemorrhage, which is a medical emergency.
    • Temporal arteritis: This condition, which typically affects older adults, can cause unilateral headaches and is a medical emergency due to the risk of vision loss if not promptly treated.
    • Brain tumor: Although rare, a brain tumor could cause localized headaches, especially if it's pressing on nerves or causing increased intracranial pressure.
  • Rare diagnoses
    • Occipital neuralgia: Involves the nerves that run from the base of the skull to the scalp and can cause severe, stabbing pain on one side of the head.
    • Hemicrania continua: A rare form of headache disorder characterized by continuous, unilateral pain.
    • Trigeminal neuralgia: While typically involving the face, in rare cases, it can cause headache-like pain on one side of the head due to the involvement of the trigeminal nerve.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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