Treatment Recommendations for Green Nail Syndrome
For green nail syndrome, daily dilute vinegar soaks (1:1 white vinegar to water) for 15 minutes twice daily is the recommended first-line treatment. 1
Understanding Green Nail Syndrome
Green nail syndrome (chloronychia) is characterized by:
- Green-yellow, green-blue, or green-brown discoloration of the nail plate
- Proximal chronic paronychia (inflammation of nail folds)
- Distal-lateral onycholysis (separation of nail from nail bed)
- Most commonly caused by Pseudomonas aeruginosa infection
Treatment Algorithm
First-Line Treatment:
Nail Preparation
Antimicrobial Soaks
Moisture Control
For Persistent Cases:
- Apply topical antibiotics (fluoroquinolones like ciprofloxacin) 5, 6
- Consider oral antibiotics (fluoroquinolones) for severe or extensive infection
- For refractory cases with significant onycholysis, chemical nail avulsion may be effective 7
Prevention Measures
- Avoid nail trauma and excessive moisture
- Properly trim nails straight across, not too short
- Wear protective gloves during wet work
- Avoid artificial nails, which are a risk factor 5
- Treat underlying nail conditions (psoriasis, etc.) that may predispose to infection
Monitoring and Follow-up
- Improvement typically begins within one week of treatment
- Complete resolution usually occurs within 8 weeks 5
- If no improvement after 2-4 weeks of treatment, consider:
- Culture to confirm diagnosis and check for resistance
- Evaluating for other underlying nail disorders
- Referral to dermatology or podiatry
Common Pitfalls
- Failing to remove the detached portion of the nail, which harbors bacteria
- Inadequate duration of treatment (must continue until complete nail regrowth)
- Not addressing underlying predisposing factors
- Missing other diagnoses that can cause nail discoloration (subungual hematoma, melanoma)
The evidence strongly supports vinegar soaks as a simple, cost-effective first-line treatment that addresses the infection while avoiding the potential side effects of systemic antibiotics. This approach has been endorsed by multiple clinical guidelines and is particularly effective when combined with proper nail trimming and moisture control.