From the Guidelines
Tirosint (Levothyroxine) is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone.
Common Uses
- Treatment of overt hypothyroidism
- Treatment of subclinical hypothyroidism, although the likelihood of improvement is considered small and should be balanced against the potential risks of therapy 1
Important Considerations
- Levothyroxine may be prescribed for patients with subclinical hypothyroidism who have symptoms compatible with hypothyroidism, but the decision to continue therapy should be based on clear symptomatic benefit 1
- The natural history of subclinical hypothyroidism and the risk of progression to overt hypothyroidism should be considered when making treatment decisions 1
From the FDA Drug Label
TIROSINT-SOL is a prescription medicine that contains a hormone called levothyroxine which is normally produced by the thyroid gland TIROSINT-SOL is used: to replace or give extra levothyroxine in people whose thyroid does not produce enough of this hormone; or with surgery and radiodine therapy to manage a type of thyroid cancer called thyroid-dependent well-differentiated thyroid cancer
Tirosint (Levothyroxine) is used for:
- Replacing or giving extra levothyroxine in people with hypothyroidism (underactive thyroid)
- Managing thyroid-dependent well-differentiated thyroid cancer with surgery and radiodine therapy 2
From the Research
Uses of Tirosint (Levothyroxine)
Tirosint, also known as levothyroxine, is used to treat various conditions related to hypothyroidism, including:
- Hypothyroidism due to total thyroidectomy 3
- Hashimoto's disease, an autoimmune thyroiditis 4
- Subclinical hypothyroidism, a biochemical condition defined by elevated serum thyroid-stimulating hormone levels 5
- Malabsorption caused by interfering diseases, drugs, and bariatric surgery 6
Patient Populations
Tirosint is used in various patient populations, including:
- Thyroidectomized patients taking proton pump inhibitors (PPIs) 3
- Patients with gastrointestinal disease, such as gastroparesis and small intestinal bacterial overgrowth (SIBO) 4
- Patients with malabsorption, including those with bariatric surgery 6
- Newborns, pregnant women, and the elderly, although particular attention must be paid to avoid over-treatment in neonates 6
Formulations
Tirosint is available in various formulations, including: