Is paradoxical adipose hyperplasia a possible complication of ultrasound-assisted lipolysis (cavitation)?

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Last updated: March 5, 2025View editorial policy

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From the Research

Paradoxical adipose hyperplasia is not typically associated with ultrasound-assisted lipolysis (cavitation) treatments, as the current evidence does not support a significant link between the two. Unlike cryolipolysis (CoolSculpting), which has documented cases of paradoxical adipose hyperplasia as a rare side effect occurring in approximately 0.05-0.39% of patients 1, ultrasound cavitation works through a different mechanism that doesn't appear to trigger this adverse reaction. The most common side effects of ultrasound cavitation include temporary redness, mild bruising, and soreness in the treated area, but not paradoxical fat growth. However, it's essential to note that while there is no direct evidence linking ultrasound cavitation to paradoxical adipose hyperplasia, cryolipolysis has been associated with this rare side effect, with an incidence rate that may be higher than initially reported 2, 3, 4. Given the differences in mechanisms between these fat reduction methods, ultrasound cavitation is not expected to cause paradoxical adipose hyperplasia, but patients should still be informed about potential risks and side effects, and treatments should be performed by qualified professionals with realistic expectations about results. Key considerations for patients undergoing ultrasound cavitation include:

  • Realistic expectations about the treatment's effectiveness for small areas of localized fat
  • Understanding of the potential, though rare, side effects
  • The importance of qualified professionals performing the treatment
  • The distinction between ultrasound cavitation and other fat reduction methods, like cryolipolysis, which have different side effect profiles.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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