Differential Diagnosis for Nodules on Shin
- Single most likely diagnosis
- Erythema nodosum: This is the most common cause of nodules on the shin, characterized by tender, erythematous nodules, often associated with an underlying infection, inflammatory condition, or medication.
- Other Likely diagnoses
- Erythema induratum: A type of panniculitis that presents with tender, nodular lesions on the lower legs, often associated with tuberculosis or other infections.
- Necrobiosis lipoidica: A condition characterized by necrotic, granulomatous lesions on the shins, often associated with diabetes.
- Granuloma annulare: A benign condition that presents with papular or nodular lesions on the skin, often on the hands and feet, but can also occur on the shins.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Subcutaneous panniculitis-like T-cell lymphoma: A rare and aggressive form of lymphoma that can present with subcutaneous nodules, including on the shins.
- Sarcoidosis: A systemic granulomatous disease that can present with skin nodules, including on the shins, and can be associated with serious internal organ involvement.
- Deep vein thrombosis: Although not typically presenting as a nodule, DVT can cause swelling and tenderness in the leg, which may be mistaken for a nodule.
- Rare diagnoses
- Rheumatoid nodules: Although more common on the hands and feet, rheumatoid nodules can occur on the shins in patients with rheumatoid arthritis.
- Xanthomas: Benign growths composed of lipid-laden macrophages, which can occur on the shins, often associated with hyperlipidemia.
- Lipodermatosclerosis: A condition characterized by induration and pigmentation of the skin on the lower legs, often associated with chronic venous insufficiency.