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Differential Diagnosis for Skin Itching and Burning Sensation

Single Most Likely Diagnosis

  • Dry Skin (Xerosis): This is often the most common cause of skin itching and burning sensation, especially in dry environments or during winter months. It's a benign condition but can significantly affect quality of life.

Other Likely Diagnoses

  • Eczema (Atopic Dermatitis): Characterized by itchy, inflamed skin, and is a common condition that can cause significant discomfort.
  • Allergic Contact Dermatitis: An allergic reaction to substances like metals, fragrances, or dyes in clothing, which can cause itching and burning sensations.
  • Psoriasis: An autoimmune condition that speeds up the life cycle of skin cells, causing cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that itch and burn.
  • Urticaria (Hives): Itchy welts that can appear anywhere on the body, often due to an allergic reaction.

Do Not Miss Diagnoses

  • Bullous Pemphigoid: An autoimmune disease that causes blistering of the skin and can be life-threatening if not treated promptly.
  • Malignancy (e.g., Lymphoma, Leukemia): Certain types of cancer can cause itching and burning sensations as an early symptom.
  • Thyroid Disorders: Both hyperthyroidism and hypothyroidism can cause skin symptoms, including itching and burning sensations.
  • Kidney or Liver Disease: Advanced kidney or liver disease can lead to itching due to the buildup of toxins in the body.

Rare Diagnoses

  • Pityriasis Rubra Pilaris: A rare skin disorder that causes constant itching and scaling (exfoliation) of the skin.
  • Sjögren's Syndrome: An autoimmune disorder that can cause skin itching and burning among other symptoms like dry eyes and mouth.
  • Brachioradial Pruritus: A rare condition characterized by intense itching on the arms, typically without a rash.
  • Aquagenic Pruritus: A condition where contact with water induces intense itching without any visible skin lesions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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