Differential Diagnosis for Transmits and Submandibular Lymphadenopathy
- Single Most Likely Diagnosis
- Tuberculosis (TB): Given the symptoms of transmits (which could imply transmission or spread of infection) and submandibular lymphadenopathy, TB is a strong candidate. TB can cause lymphadenopathy, particularly in the cervical region, including the submandibular area, and is known for its ability to spread through droplet transmission.
- Other Likely Diagnoses
- Infectious Mononucleosis: Caused by Epstein-Barr virus (EBV), this condition can lead to lymphadenopathy, including in the submandibular region, and is transmitted through saliva, mucus, and other bodily fluids.
- Toxoplasmosis: Although more commonly associated with generalized lymphadenopathy, toxoplasmosis can cause submandibular lymphadenopathy and is transmitted through contaminated food and water or from cat feces.
- Lymphoma: Both Hodgkin and non-Hodgkin lymphoma can present with lymphadenopathy, including in the submandibular region, though the transmission aspect is less clear unless considering the spread of disease.
- Do Not Miss Diagnoses
- HIV: Human Immunodeficiency Virus infection can lead to persistent generalized lymphadenopathy, including submandibular lymphadenopathy, and is critical to diagnose due to its significant impact on the immune system and the need for antiretroviral therapy.
- Cat-Scratch Disease: Caused by Bartonella henselae, this infection is transmitted through cat scratches or bites and can lead to submandibular lymphadenopathy, highlighting the importance of considering zoonotic infections.
- Sarcoidosis: Although less likely to be transmitted, sarcoidosis can cause lymphadenopathy and is a diagnosis that should not be missed due to its potential for significant morbidity if left untreated.
- Rare Diagnoses
- Kikuchi-Fujimoto Disease: A rare, self-limiting condition that can cause submandibular lymphadenopathy, its transmission or cause is not well understood, but it's essential to consider in the differential diagnosis due to its unique presentation.
- Kimura Disease: Another rare condition characterized by lymphadenopathy and eosinophilia, its transmission is not clearly defined, but it should be considered in patients with submandibular lymphadenopathy, especially in endemic areas.