From the Research
Grape seed extract does not significantly interfere with exercise adaptations, and its antioxidant properties may even provide beneficial effects on oxidative stress and physical performance, as evidenced by a 2023 study 1 that demonstrated a protective effect of grape seed extract and exercise training on tissues toxicities in doxorubicin-treated healthy rats. The current evidence suggests that grape seed extract may have a positive impact on exercise adaptations, particularly in terms of reducing oxidative stress and improving antioxidant status. A 2009 study 2 found that grape extract improved antioxidant status and physical performance in elite male athletes, while a 2019 study 3 showed that acute grape seed extract supplementation reduced muscle damage after eccentric exercise.
- The antioxidant properties of grape seed extract may help reduce muscle damage and improve recovery after exercise, as seen in the 2019 study 3 that found a significant decrease in creatine kinase levels after grape seed extract supplementation.
- Grape seed extract may also have a positive impact on cardiovascular health, as evidenced by a 2018 study 4 that found that grape seed extract supplementation attenuated the blood pressure response to exercise in prehypertensive men.
- However, it is essential to note that the current evidence is not conclusive, and more research is needed to fully understand the effects of grape seed extract on exercise adaptations.
- In terms of dosage and timing, the current evidence suggests that a dose of 300-400mg of grape seed extract may be effective in reducing oxidative stress and improving exercise performance, and that taking it at least 6-8 hours before or after exercise, or on rest days, may be beneficial.
- Ultimately, the decision to use grape seed extract as a supplement should be based on individual needs and goals, and should be made in consultation with a healthcare professional.