What are the American Family Physician's recommendations for evaluating chest pain?

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Last updated: August 4, 2025View editorial policy

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American College of Cardiology/American Heart Association Recommendations for Evaluation of Chest Pain

The evaluation of chest pain requires a focused history, physical examination, and appropriate diagnostic testing to identify potentially life-threatening causes, with an ECG obtained within 10 minutes of presentation for all patients with acute chest pain. 1

Initial Assessment and History Taking

Key Components of History

  • Characteristics of pain: Obtain detailed information about:
    • Nature (pressure, heaviness, tightness vs. sharp, stabbing)
    • Onset and duration
    • Location and radiation
    • Severity
    • Precipitating factors (exertion, emotional stress)
    • Relieving factors
    • Associated symptoms 1

Pain Descriptors and Ischemia Risk

  • Higher probability of ischemia: Central, pressure, heaviness, tightness, exertional/stress-related, retrosternal, squeezing, dull
  • Lower probability of ischemia: Stabbing, fleeting, sharp, pleuritic, positional, reproducible by palpation 1

Special Considerations for High-Risk Populations

Women

  • Women with chest pain are at risk for underdiagnosis
  • Always consider potential cardiac causes in women
  • Obtain history emphasizing accompanying symptoms more common in women with ACS 1

Older Patients (≥75 years)

  • Consider ACS when accompanying symptoms include:
    • Shortness of breath
    • Syncope
    • Acute delirium
    • Unexplained falls 1

Diverse Patient Populations

  • Use cultural competency and formal translation services when needed 1

Physical Examination

A focused cardiovascular examination should be performed to aid in diagnosis of ACS or other serious causes of chest pain and identify complications 1.

Key Physical Findings by Condition

  • ACS: Diaphoresis, tachypnea, tachycardia, hypotension, crackles, S3, MR murmur
  • Pulmonary Embolism: Tachycardia, dyspnea, pain with inspiration
  • Aortic Dissection: Pulse differential, connective tissue disorder signs
  • Pneumonia: Fever, regional dullness to percussion, egophony
  • Pneumothorax: Unilateral decreased/absent breath sounds
  • Pericarditis: Friction rub, fever, pain increased in supine position 1

Diagnostic Testing

Electrocardiogram (ECG)

  • All patients with acute chest pain: Obtain ECG within 10 minutes of arrival
  • Office setting with stable chest pain: Perform ECG unless noncardiac cause is evident
  • If ECG unavailable in office: Refer to ED for ECG 1

Cardiac Biomarkers

  • ED presentation with suspected ACS: Measure cardiac troponin (cTn) as soon as possible
  • Office setting: Avoid delayed transfer to ED for cTn testing 1

Setting-Specific Recommendations

Office/Outpatient Setting

  • For stable chest pain: Perform ECG if available
  • For suspected ACS or life-threatening causes: Transport urgently to ED via EMS
  • Avoid: Delayed transfer to ED for cardiac troponin or other diagnostic testing 1

Emergency Department

  • Obtain ECG within 10 minutes
  • Measure cardiac troponin promptly
  • Consider structured risk assessment protocols 1

Common Pitfalls to Avoid

  1. Terminology pitfall: Do not describe chest pain as "atypical" - instead, categorize as cardiac, possibly cardiac, or noncardiac 1

  2. Diagnostic pitfall: Do not use relief with nitroglycerin as a diagnostic criterion for myocardial ischemia 1

  3. Women and elderly patients: Avoid underdiagnosis by maintaining high suspicion even with less typical presentations 1

  4. Office setting: Do not delay transfer to ED when ACS is suspected 1

  5. Relying solely on chest pain history: The chest pain history alone is not sufficient to rule out ACS without appropriate diagnostic testing 2

By following these evidence-based recommendations from the American College of Cardiology/American Heart Association, clinicians can effectively evaluate chest pain and reduce morbidity and mortality from potentially life-threatening conditions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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