What is the evaluation and treatment approach for a patient presenting with right-sided pelvic pain?

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Evaluation and Treatment of Right-Sided Pelvic Pain

For patients presenting with right-sided pelvic pain, CT of the abdomen and pelvis with IV contrast is the recommended initial imaging study for non-pregnant patients, while transvaginal and transabdominal ultrasound is the first-line imaging choice for pregnant patients or when gynecologic etiology is suspected. 1

Diagnostic Approach

Initial Assessment

  • Obtain pregnancy status with β-hCG testing in all women of reproductive age before imaging 1
  • Assess for fever, leukocytosis, and specific location of pain
  • Consider both gynecologic and non-gynecologic causes:
    • Gynecologic: Ovarian cysts, adnexal torsion, PID, ectopic pregnancy
    • Non-gynecologic: Appendicitis, diverticulitis, urolithiasis, inflammatory bowel disease

Imaging Algorithm

  1. If pregnancy test positive:

    • Transvaginal and transabdominal ultrasound is first-line imaging 1
    • Avoid CT due to radiation exposure concerns
  2. If pregnancy test negative and gynecologic etiology suspected:

    • Transvaginal and transabdominal ultrasound is first-line imaging 1
    • Ultrasound findings suggestive of adnexal torsion include:
      • Enlarged ovary with stromal edema
      • Absent/diminished ovarian enhancement on Doppler
      • Peripheralized follicles
      • Tubal thickening
  3. If pregnancy test negative and non-gynecologic etiology suspected:

    • CT abdomen and pelvis with IV contrast is first-line imaging 1
    • CT has excellent diagnostic accuracy for appendicitis (95% sensitivity, 94% specificity) 1
    • CT can identify alternative diagnoses including:
      • Benign adnexal masses
      • Colitis
      • Inflammatory bowel disease
      • Constipation
      • Urolithiasis
  4. If urolithiasis is suspected:

    • Non-contrast CT abdomen and pelvis is preferred (sensitivity 97-100%) 2
    • Ultrasound with color Doppler can be considered in patients with contraindications to radiation 2

Common Pitfalls and Caveats

  • Don't miss gynecologic emergencies: Adnexal torsion and ruptured ectopic pregnancy require urgent intervention
  • Beware of normal Doppler findings: Adnexal torsion can occur despite normal vasculature on ultrasound with Doppler 3
  • Don't rely solely on clinical presentation: Misdiagnosis based on clinical assessment alone is common, with studies showing error rates of 34-68% for conditions like diverticulitis 1
  • Consider alternative diagnoses: Right colonic diverticulitis (8% of RLQ pain cases) and bowel obstruction (3% of RLQ pain cases) can mimic appendicitis 2
  • Radiation exposure: Consider ultrasound as initial imaging for young patients when appropriate to reduce radiation exposure 1

Treatment Approach

Treatment depends on the specific diagnosis:

  1. Appendicitis: Surgical consultation for appendectomy
  2. Adnexal torsion: Urgent gynecologic consultation for surgical detorsion
  3. Ovarian cysts: Conservative management for simple cysts; surgical intervention for complicated or symptomatic cysts
  4. Pelvic inflammatory disease: Antibiotic therapy; hospitalization for severe cases
  5. Urolithiasis: Pain management and hydration for stones <5mm; urologic consultation for larger stones or obstruction 2
  6. Diverticulitis: Antibiotics for uncomplicated cases; surgical consultation for complicated cases

Follow-up Recommendations

  • For patients with persistent symptoms despite negative initial imaging, consider:
    • Alternative imaging modalities (MRI for better soft tissue evaluation)
    • Gynecologic consultation for diagnostic laparoscopy if gynecologic etiology suspected
    • Urologic consultation for persistent urinary symptoms
    • Gastroenterology consultation for persistent gastrointestinal symptoms

The comprehensive evaluation of right-sided pelvic pain requires careful consideration of both gynecologic and non-gynecologic causes, with imaging selection guided by clinical suspicion and pregnancy status.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnostic Evaluation of Hematuria and Flank Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Acute Pelvic Pain.

Emergency medicine clinics of North America, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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