Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a 1-Month-Old Cross-Eyed Infant

Single Most Likely Diagnosis

  • Infantile Esotropia: This condition is a common cause of crossed eyes in infants, often appearing in the first few months of life. It's characterized by an inward deviation of the eyes and can be associated with other ocular and systemic conditions.

Other Likely Diagnoses

  • Accommodative Esotropia: Although less common in infants as young as one month, this condition can occur if there's a significant refractive error that causes the eyes to turn inward to focus.
  • Nasolacrimal Duct Obstruction: While not directly causing crossed eyes, the constant tearing and irritation from a blocked tear duct can lead to a pseudostrabismus appearance or contribute to the development of actual strabismus due to chronic eye rubbing.
  • Pseudostrabismus: This condition gives the appearance of crossed eyes due to the shape of the face or the presence of a wide nasal bridge, but the eyes are actually aligned properly when examined closely.

Do Not Miss Diagnoses

  • Retinoblastoma: Although rare, this serious eye cancer can cause strabismus (crossed eyes) among other symptoms like leukocoria (a white reflex in the pupil). Early detection is crucial for treatment and survival.
  • Cataracts: Congenital cataracts can cause visual deprivation, leading to strabismus or nystagmus. Prompt diagnosis and treatment are necessary to prevent long-term vision problems.
  • Glaucoma: Infantile glaucoma can cause enlarged eyes, tearing, and light sensitivity, and if not treated, can lead to vision loss and potentially strabismus.

Rare Diagnoses

  • Duane Syndrome: A rare congenital disorder characterized by limited horizontal eye movement, which can cause esotropia (crossed eyes) or exotropia (outward turning eyes).
  • Moebius Syndrome: A rare neurological disorder that can cause facial paralysis and impaired eye movements, potentially leading to crossed eyes.
  • Congenital Cranial Nerve Palsies: Abnormalities in the nerves that control eye movement can result in strabismus. These are rare and often associated with other systemic conditions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.