Differential Diagnosis for Crack Corners of Mouth
- Single most likely diagnosis
- Angular cheilitis: This condition is characterized by inflammation of the corners of the mouth, often causing cracks and fissures. It is commonly seen in individuals with poor oral hygiene, nutritional deficiencies, or those who wear ill-fitting dentures.
- Other Likely diagnoses
- Dry mouth (xerostomia): Reduced saliva production can lead to dry, cracked lips and corners of the mouth.
- Contact dermatitis: Irritation from certain substances like food, cosmetics, or oral care products can cause inflammation and cracking at the corners of the mouth.
- Vitamin deficiencies (e.g., vitamin B2, vitamin B12, or iron): Deficiencies in these vitamins can lead to various oral manifestations, including cracks at the corners of the mouth.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Oral cancer: Although less common, oral cancer can manifest as persistent cracks or ulcers at the corners of the mouth, emphasizing the importance of thorough examination and follow-up.
- Infections (e.g., syphilis, tuberculosis): Certain infections can cause oral lesions, including cracks at the corners of the mouth, and require prompt diagnosis and treatment.
- Rare diagnoses
- Sjögren's syndrome: An autoimmune disorder that can cause dry mouth and other oral symptoms, including cracks at the corners of the mouth.
- Gastroesophageal reflux disease (GERD): Stomach acid reflux can sometimes cause irritation and cracking at the corners of the mouth.
- Actinic cheilitis: A condition caused by prolonged sun exposure, leading to dry, cracked lips and corners of the mouth.