Revised Cardiac Risk Index (RCRI) Conditions and Preoperative Management
The Revised Cardiac Risk Index (RCRI) comprises six independent clinical risk factors that predict perioperative cardiac complications: history of ischemic heart disease, history of congestive heart failure, history of cerebrovascular disease, insulin-dependent diabetes mellitus, preoperative serum creatinine >2.0 mg/dL, and high-risk type of surgery. 1
RCRI Conditions in Detail
1. History of Ischemic Heart Disease
- Defined as 1:
- History of myocardial infarction
- History of positive treadmill test
- Current use of nitroglycerin
- Chest pain considered secondary to coronary ischemia
- ECG with abnormal Q waves
2. History of Congestive Heart Failure
- Defined as 1:
- History of heart failure
- Pulmonary edema
- Paroxysmal nocturnal dyspnea
- Peripheral edema
- Bilateral rales
- S3 heart sound
- Chest radiograph showing pulmonary vascular redistribution
3. History of Cerebrovascular Disease
- Defined as 1:
- History of transient ischemic attack (TIA)
- History of stroke
4. Preoperative Insulin Treatment for Diabetes Mellitus
- Specifically insulin-dependent diabetes 1
5. Preoperative Serum Creatinine >2.0 mg/dL (>177 μmol/L)
- Indicates significant renal dysfunction 1
- Note: More recent evidence suggests that using GFR <30 mL/min may be a better predictor than the creatinine cutoff 2
6. High-Risk Type of Surgery
- Includes 1:
- Intraperitoneal procedures
- Intrathoracic procedures
- Suprainguinal vascular surgery
Risk Stratification Based on RCRI
The risk of major cardiac complications increases with the number of risk factors 1, 3:
- 0 risk factors: 0.4-0.5% risk
- 1 risk factor: 0.9-1.3% risk
- 2 risk factors: 4-7% risk
- ≥3 risk factors: 9-11% risk
Preoperative Management Based on RCRI
Step 1: Determine Urgency of Surgery
- For emergency surgery: Limited evaluation; focus on perioperative medical management and surveillance 1
- For elective surgery: Proceed with systematic risk assessment 1
Step 2: Identify Active Cardiac Conditions
- Presence of any of these conditions may require delay or cancellation of surgery 1:
- Unstable coronary syndromes
- Decompensated heart failure
- Significant arrhythmias
- Severe valvular disease
Step 3: Assess RCRI Risk Factors
- Count the number of RCRI risk factors present 1
Step 4: Management Based on Risk Level
Low Risk (0 Risk Factors)
- Proceed with planned surgery
- No additional cardiac testing needed 1
Intermediate Risk (1-2 Risk Factors)
- Consider functional capacity assessment
- For patients with poor functional capacity undergoing vascular surgery:
- Consider non-invasive cardiac testing if it will change management 1
- Consider perioperative beta-blockade for appropriate patients 1
High Risk (≥3 Risk Factors)
- Consider non-invasive cardiac testing if it will change management
- Consider cardiology consultation
- Consider perioperative beta-blockade 1
Step 5: Specific Management for Each RCRI Condition
Ischemic Heart Disease
- Optimize anti-anginal medications
- Consider stress testing for patients with poor functional capacity
- For recent MI, wait 4-6 weeks before elective surgery if possible 1
Heart Failure
- Ensure optimal medical therapy and euvolemic status
- Consider preoperative echocardiography to assess ventricular function 1
Cerebrovascular Disease
- Continue antiplatelet therapy unless bleeding risk is prohibitive
- Consider carotid evaluation if symptomatic carotid disease present 1
Insulin-Dependent Diabetes
- Maintain glycemic control
- Monitor glucose levels perioperatively
- Develop protocol for insulin management during perioperative period 1
Renal Insufficiency
- Optimize volume status
- Avoid nephrotoxic medications
- Consider renal consultation for severe dysfunction 1
Important Considerations and Caveats
- The RCRI is most validated for patients undergoing elective non-cardiac surgery 3
- The RCRI may underestimate risk in vascular surgery patients 1
- Age is not included in the RCRI but is an independent predictor of perioperative risk 1, 4
- Recent evidence suggests that using GFR <30 mL/min instead of creatinine >2.0 mg/dL improves risk prediction 2
- Emergency surgery significantly increases risk beyond what the RCRI predicts 5
- Anemia (hematocrit <28%) can increase perioperative cardiac risk and should be addressed 1
By systematically evaluating these six RCRI factors and implementing appropriate management strategies, perioperative cardiac risk can be effectively minimized to improve patient outcomes.