How to administer Baqsimi (somatropin) nasal spray?

How to Administer Baqsimi Nasal Spray

Baqsimi nasal spray (glucagon) should be administered by inserting the tip into one nostril and pressing the plunger completely to deliver the full 3 mg dose, without requiring inhalation, for emergency treatment of severe hypoglycemia.

Understanding Baqsimi

Baqsimi is a nasal formulation of glucagon used for emergency treatment of severe hypoglycemia in people with diabetes. Unlike traditional injectable glucagon, Baqsimi offers a needle-free alternative that can be administered by caregivers or family members during hypoglycemic emergencies.

Key features:

• Single-use device containing 3 mg of glucagon
• Does not require reconstitution (ready to use)
• Does not require inhalation to be effective
• Stable at room temperature

Step-by-Step Administration Technique

1. Preparation:

   • Remove the shrink wrap by pulling on the red stripe
   • Open the tube and remove the device

2. Positioning:

   • Hold the device between fingers and thumb
   • Do NOT push the plunger yet
   • Do NOT test or prime the device before use

3. Administration:

   • Insert the tip gently into one nostril
   • Keep the head in an upright position
   • Press the plunger completely with your thumb
   • The dose is complete when the green line is no longer visible

4. Post-administration:

   • The full dose is delivered in just one nostril (do not use in both nostrils)
   • The person does not need to inhale or breathe deeply
   • Call for emergency medical help immediately after administration
   • Turn the unconscious person to their side to prevent choking
   • When the person regains consciousness, give them a fast-acting source of sugar followed by a longer-acting carbohydrate

Important Considerations

• Baqsimi is effective even if the person is unconscious or having a seizure
• The device delivers a fixed dose of 3 mg glucagon and cannot be adjusted
• Unlike nasal steroid sprays 1, Baqsimi does not require special head positioning or breathing techniques
• Baqsimi can be used in children and adults with diabetes at risk for severe hypoglycemia 2
• The device is single-use only and cannot be reused

Advantages Over Injectable Glucagon

Studies have shown that nasal glucagon administration is as effective as injectable glucagon but is preferred by caregivers due to:

• No need for reconstitution
• Easier and quicker administration
• Less intimidating for non-medical caregivers
• Reduced delay in treatment during emergencies 2

Storage and Handling

• Store at room temperature (up to 30°C/86°F)
• Keep in the original shrink-wrapped tube until ready to use
• Check expiration date before use
• Do not attempt to test the device before actual use

Remember that Baqsimi is for emergency use only and should be followed by immediate medical attention. Caregivers and family members of people with diabetes should be trained on proper administration technique before an emergency occurs.