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Last updated: August 6, 2025View editorial policy

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Differential Diagnosis for Penile Body Swollen

  • Single most likely diagnosis
    • Balanitis: This is an inflammation of the glans (the rounded head of the penis) and is often associated with swelling. It's commonly caused by poor hygiene, infections (bacterial, fungal, or viral), or allergic reactions. Given its prevalence and direct relation to penile swelling, it stands as a highly probable diagnosis.
  • Other Likely diagnoses
    • Phimosis: A condition where the foreskin cannot be fully retracted over the glans. This can lead to swelling due to trapped moisture and potential infection. It's a common issue, especially in uncircumcised males, and can cause noticeable swelling.
    • Penile fracture: Although more associated with trauma and pain, a penile fracture can cause significant swelling of the penile body. It's a condition that requires immediate medical attention.
    • Cellulitis: A bacterial skin infection that can cause redness, swelling, and warmth of the skin. If it affects the penile area, it could lead to swelling of the penile body.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Necrotizing fasciitis: A severe infection that destroys tissue under the skin, including fat and the tissue covering the muscles (fascia). It's rare but can be fatal if not treated promptly. Swelling, pain, and discoloration are symptoms.
    • Penile cancer: Although rare, penile cancer can cause swelling among other symptoms like sores or lesions. Early detection is crucial for effective treatment.
  • Rare diagnoses
    • Lymphogranuloma venereum (LGV): A sexually transmitted infection caused by certain types of the bacteria Chlamydia trachomatis. It can cause swelling and other symptoms in the genital area.
    • Fournier's gangrene: A rare but serious condition characterized by necrotizing fasciitis of the genitalia. It's more common in men and can start with swelling, pain, and redness of the genital area, progressing rapidly.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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