Postoperative Care After Hysteroscopic Polypectomy
Patients should be provided with written information about the risk of post-procedure complications (including bleeding risk for up to 2 weeks), along with recommended actions and an emergency contact number to ensure prompt management of any complications. 1
Monitoring for Potential Complications
Bleeding
- Delayed bleeding is the most common complication after polypectomy procedures
- Patients should be informed that bleeding may occur up to 17 days after the procedure, with mean presentation time of 5 days 1
- Normal post-procedure spotting should be distinguished from significant hemorrhage requiring medical attention
- Risk factors for post-polypectomy bleeding include:
- Large polyp size
- Multiple polyps
- Use of anticoagulants or antiplatelet medications
Post-Polypectomy Coagulation Syndrome
- Symptoms include fever, localized abdominal tenderness (often with rebound), and leukocytosis occurring within hours to days after polypectomy 1
- Management includes:
- Close observation by medical team
- Intravenous fluids
- Antibiotics
- Bowel rest
Perforation
- Although rare, this is the most serious complication
- Symptoms may present immediately or be delayed up to 15 days after the procedure 1
- Patients should seek immediate medical attention for severe abdominal pain, distension, fever, or signs of peritonitis
Medication Management
Anticoagulant and Antiplatelet Therapy
- Resumption of anticoagulant and anti-platelet therapy should be considered on an individual basis, weighing the risks of post-procedure bleeding against the risks of thromboembolic events 1
- Conflicting evidence exists regarding the safety of restarting anticoagulants:
- For patients on DOACs (Direct Oral Anticoagulants), resumption timing should be individualized based on bleeding risk assessment 1
Antibiotics
- Routine antibiotic therapy after uncomplicated hysteroscopic polypectomy is not necessary
- Evidence suggests that hysteroscopic polypectomy alone without antibiotics may be more effective for treating chronic endometritis with endometrial polyps 2
Follow-up Recommendations
Initial Follow-up Timing
- For piecemeal removal of polyps, initial follow-up should take place within 2-6 months 1
- Early follow-up is important due to potentially high rates of incomplete resection and early recurrence 1
- Recurrence rates increase with longer follow-up periods (18.4% at 6 months, 23.1% at 12 months, and 30.7% at 24 months) 1
Risk Factors for Polyp Recurrence
- Higher number of endometrial polyps is associated with increased recurrence risk 3
- Longer duration of follow-up correlates with higher recurrence potential 3
- Resectoscopic polypectomy techniques have lower recurrence rates (0%) compared to grasping forceps techniques (15%) 4
Patient Instructions
Activity Restrictions:
- Light activity for 24-48 hours
- Avoid strenuous activity for 1 week
- Resume normal activities gradually as tolerated
Hygiene and Sexual Activity:
- Avoid sexual intercourse, douching, and tampon use for 2 weeks to reduce infection risk
- Shower normally but avoid baths for 1 week
When to Seek Medical Attention:
- Heavy bleeding (soaking through a pad in less than an hour)
- Severe abdominal pain
- Fever over 100.4°F (38°C)
- Foul-smelling vaginal discharge
- Signs of infection
Special Considerations
For Fertility Patients
- Hysteroscopic polypectomy appears to improve fertility and increase pregnancy rates in previously infertile women, regardless of polyp size or number 5
- Spontaneous pregnancy rates of 61.4% have been reported after polypectomy in infertile women with endometrial polyps 5
- Restoration of reproductive ability does not depend on the size of the removed polyp 4
For Patients with Abnormal Uterine Bleeding
- Normalization of menstrual patterns occurs in 91.6-93.1% of patients following polypectomy 5, 4
- Pedunculated polyps are more closely associated with abnormal uterine bleeding 3
By following these comprehensive postoperative care instructions, patients can minimize complications and optimize outcomes after hysteroscopic polypectomy.