From the Research
Mildly decreased testosterone levels in females should be addressed through lifestyle modifications and, if necessary, low-dose testosterone therapy under medical supervision, as it plays a crucial role in maintaining sexual function, bone density, and overall well-being, as supported by the most recent guideline from 2021 1.
Implications of Low Testosterone in Women
The implications of mildly decreased testosterone levels in females can be significant, affecting not only sexual function but also overall quality of life. Testosterone is essential for women's health, contributing to libido, energy levels, and bone density. Symptoms of low testosterone in women may include decreased sexual desire, fatigue, and mood changes.
Lifestyle Modifications
Before considering medical treatment, lifestyle changes can be beneficial:
- Regular exercise, particularly strength training 2-3 times weekly
- Maintaining a balanced diet rich in zinc and vitamin D
- Managing stress through meditation or yoga
- Ensuring 7-9 hours of quality sleep nightly
Medical Treatment
If symptoms persist, medical treatments might include:
- Testosterone supplements in various forms (gels, creams, or patches) at low doses specifically formulated for women, typically 0.5-2 mg daily depending on the preparation
- These treatments should only be used under medical supervision due to potential side effects like acne, hair growth, or voice deepening
Importance of Monitoring
Regular monitoring is essential if supplementation is prescribed to ensure levels remain appropriate, as supported by the guideline from 2021 1. This includes assessing for signs of androgen excess and monitoring total testosterone levels to maintain concentrations in the physiologic premenopausal range.
Key Considerations
- Testosterone therapy is not approved for women by most regulatory agencies, making prescribing and proper dosing challenging
- Compounded products cannot be recommended due to the lack of efficacy and safety data
- Government-approved transdermal male formulations can be used cautiously with dosing appropriate for women, as suggested by the guideline 1